SURVEY OF PREDICTIVE VALUE OF 4-HOUR URINE COLLECTION FOR DIAGNOSIS OF PROTEINURIA IN PREECLAMPSIA

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ASGHARNIA MARYAM; FARAJI ROYA; MIRHAGHJOO NOOSHAZ; ATRKAR ROSHAN ZAHRA; ASHRAFKHANI BABAK; MOSLEHI MINA

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Journal: International Journal of Reproductive BioMedicine Year:2013 | Volume:11 | Issue:8 Page(s): 647-652

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Title

SURVEY OF PREDICTIVE VALUE OF 4-HOUR URINE COLLECTION FOR DIAGNOSIS OF PROTEINURIA IN PREECLAMPSIA

Author(s)

Keywords

PREECLAMPSIA

PROTEINURIA

GESTATIONAL HYPERTENSION

Abstract

Background: Measuring the 24-hour urine protein ≥300 mg is the standard threshold value for diagnosis of PREECLAMPSIA.Objective: This study was intended to determine if a patient’s 4-hour urine protein correlate with the 24-hour value for diagnosis of PREECLAMPSIA.Materials and Methods: This was a cross sectional study performed on 84 women with suspected PREECLAMPSIA due to positive urinary test strip with minimum protein content of 1+ and BP ≥140/90 at Al-zahra Educational Hospital in Rasht (Iran) from May 2007 to January 2008. Urine samples were collected within 24 hours in successive periods: The first 4-hour and the next 20-hours urine, in separate containers. The protein contents of 4-hour and 24-hour urine samples were calculated. Data were analyzed by intra-class correlation coefficient, and Receiver Operating Characteristic (ROC) curve.Results: The ROC curve showed the cut-off point of 55.5 for 4-hour urine protein. The correlation between 4- and 24-hour urine protein excretions identified that most women (about 85.1%) with protein excretion rate of 300 mg/24h or more (with PREECLAMPSIA) had the same amount of protein of 55.5 or more in their 4-hour urine excretion (p<0.001). Also, most of them (about 83.7%) with a total urinary protein excretion of less than 300 mg/24h (no PREECLAMPSIA) had a protein excretion rate of less than 55.5 mg/4h.Conclusion: This study showed 4-hour protein collection can be used as acceptable substitute for assessing the protein content of 24-hour urine samples as a more convenient, faster, and cheaper method for diagnosis of PREECLAMPSIA and the cut-off point for 4-hour urine protein is 55.5 mg.

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APA: Copy

ASGHARNIA, MARYAM, FARAJI, ROYA, MIRHAGHJOO, NOOSHAZ, ATRKAR ROSHAN, ZAHRA, ASHRAFKHANI, BABAK, & MOSLEHI, MINA. (2013). SURVEY OF PREDICTIVE VALUE OF 4-HOUR URINE COLLECTION FOR DIAGNOSIS OF PROTEINURIA IN PREECLAMPSIA. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 11(8), 647-652. SID. https://sid.ir/paper/296113/en

Vancouver: Copy

ASGHARNIA MARYAM, FARAJI ROYA, MIRHAGHJOO NOOSHAZ, ATRKAR ROSHAN ZAHRA, ASHRAFKHANI BABAK, MOSLEHI MINA. SURVEY OF PREDICTIVE VALUE OF 4-HOUR URINE COLLECTION FOR DIAGNOSIS OF PROTEINURIA IN PREECLAMPSIA. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2013;11(8):647-652. Available from: https://sid.ir/paper/296113/en

IEEE: Copy

MARYAM ASGHARNIA, ROYA FARAJI, NOOSHAZ MIRHAGHJOO, ZAHRA ATRKAR ROSHAN, BABAK ASHRAFKHANI, and MINA MOSLEHI, “SURVEY OF PREDICTIVE VALUE OF 4-HOUR URINE COLLECTION FOR DIAGNOSIS OF PROTEINURIA IN PREECLAMPSIA,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 11, no. 8, pp. 647–652, 2013, [Online]. Available: https://sid.ir/paper/296113/en

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