POST-TREATMENT WITH TELFAIRIA OCCIDENTALIS SEED OIL ATTENUATES ALCOHOL-INDUCED TESTICULAR DAMAGE IN SPRAGUE-DAWLEY RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

AYODELE OREMOSU ADEMOLA; AKANG EDIDIONG NNAMSO; ADIGWE CATHERINE CHUKWUMUANYA; OKOKO INIEBEHE ESSIEN; AZU ONYEMAECHI OKPARA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: International Journal of Reproductive BioMedicine Year:2013 | Volume:11 | Issue:8 Page(s): 637-646

Download Full-Text

View:

326

Download:

108

Cites:

Information Journal Paper

Title

POST-TREATMENT WITH TELFAIRIA OCCIDENTALIS SEED OIL ATTENUATES ALCOHOL-INDUCED TESTICULAR DAMAGE IN SPRAGUE-DAWLEY RATS

Author(s)

Keywords

TELFAIRIA OCCIDENTALIS

TESTIS

HISTOLOGY

TOXICITY

SPERM COUNT

Abstract

Background: Long term alcohol use has been implicated in men with sexual disorders including suppression of testosterone levels as well as testicular morphological changes.Objective: This research investigated the ability of TELFAIRIA OCCIDENTALIS (T.O.) to attenuate the damaging effects of alcohol on the testicular parameters. Materials and Methods: Thirty male Sprague-Dawley rats, 170-190 grams were divided into 6 groups, A to F and treated with distilled water (DW) for the period of 8 weeks (positive control group A), ethanol for 2 weeks followed with DW for 6 weeks (group B) (negative control), ethanol alone for 2 weeks (group C) while others received ethanol for 2 weeks, followed with 200 (group D), 400 (group E) and 600 mg/kg (group F) of T.O. for 6 weeks.Results: Testicular histological sections showed that ethanol produced marked loss of testicular germ cells after two weeks of administration. T.O (200 mg/kg body weight) was not able to attenuate this microanatomical distortion when compared with control groups, but at 400 mg/kg body weight, T.O reversed the ethanol`s effects with resultant significant increase in SPERM COUNT and motility (p<0.05), serum testosterone levels (p<0.05), and testicular weight (p<0.05). However, at 600 mg/kg dosage, there was marked depletion of testicular germ cells with atrophied seminiferous tubules and a decrease in semen parameters and testicular weight.Conclusion: Our result suggests that T.O promotes the regeneration of testicular germ cells and improves semen quality at a certain critical dose. Hence, T.O has a potential of reversing ethanol induced testicular damage.

Cites

No record.

References

No record.

Cite

APA: Copy

AYODELE, OREMOSU ADEMOLA, AKANG, EDIDIONG NNAMSO, ADIGWE, CATHERINE CHUKWUMUANYA, OKOKO, INIEBEHE ESSIEN, & AZU, ONYEMAECHI OKPARA. (2013). POST-TREATMENT WITH TELFAIRIA OCCIDENTALIS SEED OIL ATTENUATES ALCOHOL-INDUCED TESTICULAR DAMAGE IN SPRAGUE-DAWLEY RATS. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 11(8), 637-646. SID. https://sid.ir/paper/296117/en

Vancouver: Copy

AYODELE OREMOSU ADEMOLA, AKANG EDIDIONG NNAMSO, ADIGWE CATHERINE CHUKWUMUANYA, OKOKO INIEBEHE ESSIEN, AZU ONYEMAECHI OKPARA. POST-TREATMENT WITH TELFAIRIA OCCIDENTALIS SEED OIL ATTENUATES ALCOHOL-INDUCED TESTICULAR DAMAGE IN SPRAGUE-DAWLEY RATS. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2013;11(8):637-646. Available from: https://sid.ir/paper/296117/en

IEEE: Copy

OREMOSU ADEMOLA AYODELE, EDIDIONG NNAMSO AKANG, CATHERINE CHUKWUMUANYA ADIGWE, INIEBEHE ESSIEN OKOKO, and ONYEMAECHI OKPARA AZU, “POST-TREATMENT WITH TELFAIRIA OCCIDENTALIS SEED OIL ATTENUATES ALCOHOL-INDUCED TESTICULAR DAMAGE IN SPRAGUE-DAWLEY RATS,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 11, no. 8, pp. 637–646, 2013, [Online]. Available: https://sid.ir/paper/296117/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops