مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

LACK OF ASSOCIATION OF DRD3 AND CNR1 POLYMORPHISMS WITH PREMENSTRUAL DYSPHORIC DISORDERS

Pages

  221-226

Abstract

 Background: Premenstrual dysphoric disorder (PMDD) is a mood disorder characterized with physical and affective symptoms during the luteal phase of susceptible women.Objective: The aim of this study was to investigate the association of DOPAMINE D3 RECEPTOR (DRD3) polymorphism, and CANNABINOID RECEPTOR Type 1 (CNR1) polymorphism with PMDD.Materials and Methods: Fifty one participants with documented PMDD according to the DSM IV criteria and 51 healthy controls were included in this cross sectional study. Symptom severity was measured with daily self-rating, monthly premenstrual assessment forms and psychiatric interviews. The genotyping of DRD3 receptor and Cannabinoid type 1 receptors were performed using Taqmanfluorogenic assay method.Results: Distribution of DRD3 and CNR1 polymorphism was not different between patients and controls.Conclusion: These findings do not support a major role of DRD3, and CNR1 polymorphisms in contributing to susceptibility to premenstrual dysphoric disorder.

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    APA: Copy

    YILDIZ, MESUT, VURAL, MEHMET, ERDAL, MEHMET EMIN, AY, OZLEM IZCI, YILMAZ, SENAY GORUCU, KARABABA, IBRAHIM FATIH, & SELEK, SALIH. (2015). LACK OF ASSOCIATION OF DRD3 AND CNR1 POLYMORPHISMS WITH PREMENSTRUAL DYSPHORIC DISORDERS. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 13(4), 221-226. SID. https://sid.ir/paper/296209/en

    Vancouver: Copy

    YILDIZ MESUT, VURAL MEHMET, ERDAL MEHMET EMIN, AY OZLEM IZCI, YILMAZ SENAY GORUCU, KARABABA IBRAHIM FATIH, SELEK SALIH. LACK OF ASSOCIATION OF DRD3 AND CNR1 POLYMORPHISMS WITH PREMENSTRUAL DYSPHORIC DISORDERS. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2015;13(4):221-226. Available from: https://sid.ir/paper/296209/en

    IEEE: Copy

    MESUT YILDIZ, MEHMET VURAL, MEHMET EMIN ERDAL, OZLEM IZCI AY, SENAY GORUCU YILMAZ, IBRAHIM FATIH KARABABA, and SALIH SELEK, “LACK OF ASSOCIATION OF DRD3 AND CNR1 POLYMORPHISMS WITH PREMENSTRUAL DYSPHORIC DISORDERS,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 13, no. 4, pp. 221–226, 2015, [Online]. Available: https://sid.ir/paper/296209/en

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