REVIEW ARTICLE: ETIOLOGIES OF SPERM OXIDATIVE STRESS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

SABETI PARVIN; POURMASOUMI SOHEILA; RAHIMINIA TAHEREH; AKYASH FATEMEH; TALEBI ALI REZA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: International Journal of Reproductive BioMedicine Year:2016 | Volume:14 | Issue:4 Page(s): 231-240

Download Full-Text

View:

458

Download:

128

Cites:

Information Journal Paper

Title

REVIEW ARTICLE: ETIOLOGIES OF SPERM OXIDATIVE STRESS

Author(s)

Keywords

OXIDATIVE STRESS

SPERM

REACTIVE OXYGEN SPECIES

ETIOLOGY

Abstract

Sperm is particularly susceptible to REACTIVE OXYGEN SPECIES (ROS) during critical phases of SPERMiogenesis. However, the level of seminal ROS is restricted by seminal antioxidants which have beneficial effects on SPERM parameters and developmental potentials. Mitochondria and SPERM plasma membrane are two major sites of ROS generation in SPERM cells. Besides, leukocytes including polymer phonuclear (PMN) leukocytes and macrophages produce broad category of molecules including oxygen free radicals, non-radical species and reactive nitrogen species. Physiological role of ROS increase the intracellular cAMP which then activate protein kinase in male reproductive system. This indicates that SPERMatozoa need small amounts of ROS to acquire the ability of nuclear maturation regulation and condensation to fertilize the oocyte. There is a long list of intrinsic and extrinsic factors which can induce OXIDATIVE STRESS to interact with lipids, proteins and DNA molecules. As a result, we have lipid peroxidation, DNA fragmentation, axonemal damage, denaturation of the enzymes, over generation of superoxide in the mitochondria, lower antioxidant activity and finally abnormal SPERMatogenesis. If OXIDATIVE STRESS is considered as one of the main cause of DNA damage in the germ cells, then there should be good reason for antioxidant therapy in these conditions.

Cites

References

No record.

Cite

APA: Copy

SABETI, PARVIN, POURMASOUMI, SOHEILA, RAHIMINIA, TAHEREH, AKYASH, FATEMEH, & TALEBI, ALI REZA. (2016). REVIEW ARTICLE: ETIOLOGIES OF SPERM OXIDATIVE STRESS. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 14(4), 231-240. SID. https://sid.ir/paper/296259/en

Vancouver: Copy

SABETI PARVIN, POURMASOUMI SOHEILA, RAHIMINIA TAHEREH, AKYASH FATEMEH, TALEBI ALI REZA. REVIEW ARTICLE: ETIOLOGIES OF SPERM OXIDATIVE STRESS. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2016;14(4):231-240. Available from: https://sid.ir/paper/296259/en

IEEE: Copy

PARVIN SABETI, SOHEILA POURMASOUMI, TAHEREH RAHIMINIA, FATEMEH AKYASH, and ALI REZA TALEBI, “REVIEW ARTICLE: ETIOLOGIES OF SPERM OXIDATIVE STRESS,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 14, no. 4, pp. 231–240, 2016, [Online]. Available: https://sid.ir/paper/296259/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops