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Information Journal Paper

Title

Efficacy of Intrauterine infusion of granulocyte colony stimulating factor on patients with history of implantation failure: A randomized control trial

Pages

  687-690

Abstract

 Background: Although Pregnancy rate in In vitro fertilization-embryo transfer (IVF-ET) cycles has been increased over the preceding years, but the majority of IVF-ET cycles still fail. Granulocyte colony stimulating factor (GCSF) is a glycoprotein that stimulates cytokine growth factor and induces immune system which may improve Pregnancy rate in women with history of implantation failure. Objective: The aim of this study was to evaluate GCSF ability to improve Pregnancy rate in women with history of implantation failure Materials and Methods: 0. 5 ml (300 μ g/ml) GCSF was infused intrauterine in intervention group. Pregnancy outcomes were assessed based on clinical pregnancy. Results: The mean age of participants was 31. 95± 4. 71 years old. There were no significant differences between demographic characteristics in two groups (p>0. 05). The pregnancy outcome in GCSF group was improved significantly (p=0. 043). Conclusion: GCSF can improve pregnancy outcome in patients with history of implantation failure.

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    APA: Copy

    EFTEKHAR, MARYAM, MIRAJ, SEPIDEH, FARID MOJTAHEDI, MARYAM, & NEGHAB, NOSRAT. (2016). Efficacy of Intrauterine infusion of granulocyte colony stimulating factor on patients with history of implantation failure: A randomized control trial. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 14(11), 687-690. SID. https://sid.ir/paper/296398/en

    Vancouver: Copy

    EFTEKHAR MARYAM, MIRAJ SEPIDEH, FARID MOJTAHEDI MARYAM, NEGHAB NOSRAT. Efficacy of Intrauterine infusion of granulocyte colony stimulating factor on patients with history of implantation failure: A randomized control trial. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2016;14(11):687-690. Available from: https://sid.ir/paper/296398/en

    IEEE: Copy

    MARYAM EFTEKHAR, SEPIDEH MIRAJ, MARYAM FARID MOJTAHEDI, and NOSRAT NEGHAB, “Efficacy of Intrauterine infusion of granulocyte colony stimulating factor on patients with history of implantation failure: A randomized control trial,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 14, no. 11, pp. 687–690, 2016, [Online]. Available: https://sid.ir/paper/296398/en

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