Triage by cervical length sonographic measurements for targeted therapy in threatened preterm labor: A double blind randomized clinical trial

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VAFAEI HOMEIRA; Rahimirad Neda; Hosseini Seyedeh Marjan; KASRAEIAN MARYAM; ASADI NASRIN; Raeisi Shahraki Hadi; Bazrafshan Khadijeh

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Journal: International Journal of Reproductive BioMedicine Year:2017 | Volume:15 | Issue:11 Page(s): 697-702

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Title

Triage by cervical length sonographic measurements for targeted therapy in threatened preterm labor: A double blind randomized clinical trial

Author(s)

Keywords

Cervical length

Preterm labor

Tocolysis

Ultrasonography

Abstract

Background: Preterm labor and birth are associated with several neonatal complications including respiratory distress syndrome and intraventricular hemorrhage. Differentiating true and false labor pain is a dilemma to obstetricians. Objective: To elucidate the role of Cervical length measurement in prediction of birth in pregnant women with threatened Preterm labor. Materials and Methods: In this double blind randomized clinical trial, 120 women with gestational age <34 wk who presented painful uterine contractions randomly assigned to undergo measurement of Cervical length. Patients were registered in the hospital and a unit number was given. Based on the unit numbers, patients were randomly assigned to two groups using a computerized random digit generator. All participants were managed accordingly (n=65) or to receive Tocolysis as planned (n=55). Tocolysis was prescribed when Cervical length was <15 mm while those with Cervical length ≥ 15 mm were managed expectantly. Delivery within 7 days of the presentation was the primary outcome. Results: This RCT showed in case group, 78. 9% of patient with Cervical length <15 mm were delivered within 7 days and only 21. 1% of them maintained their pregnancy. Of those with Cervical length ≥ 15 mm, only 15. 2% were delivered within the study period and the rest (84. 8%) maintained their pregnancy (p<0. 001). Conclusion: “ Our results indicate that in women who presented Preterm labor symptoms, Cervical length measurement will result in decreased unnecessary tocolytic treatment. Women with Cervical length ≥ 15mm should not receive Tocolysis, however, withholding corticosteroid therapy in these patients needs further evidence.

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APA: Copy

VAFAEI, HOMEIRA, Rahimirad, Neda, Hosseini, Seyedeh Marjan, KASRAEIAN, MARYAM, ASADI, NASRIN, Raeisi Shahraki, Hadi, & Bazrafshan, Khadijeh. (2017). Triage by cervical length sonographic measurements for targeted therapy in threatened preterm labor: A double blind randomized clinical trial. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 15(11), 697-702. SID. https://sid.ir/paper/296463/en

Vancouver: Copy

VAFAEI HOMEIRA, Rahimirad Neda, Hosseini Seyedeh Marjan, KASRAEIAN MARYAM, ASADI NASRIN, Raeisi Shahraki Hadi, Bazrafshan Khadijeh. Triage by cervical length sonographic measurements for targeted therapy in threatened preterm labor: A double blind randomized clinical trial. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2017;15(11):697-702. Available from: https://sid.ir/paper/296463/en

IEEE: Copy

HOMEIRA VAFAEI, Neda Rahimirad, Seyedeh Marjan Hosseini, MARYAM KASRAEIAN, NASRIN ASADI, Hadi Raeisi Shahraki, and Khadijeh Bazrafshan, “Triage by cervical length sonographic measurements for targeted therapy in threatened preterm labor: A double blind randomized clinical trial,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 15, no. 11, pp. 697–702, 2017, [Online]. Available: https://sid.ir/paper/296463/en

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