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Information Journal Paper

Title

Comparison of Chlamydia trachomatis infection among infertile and fertile women in Ahvaz, Iran: A casecontrol study

Pages

  713-718

Abstract

 Background: Chlamydia trachomatis (C. trachomatis) is the main cause of bacterial sexually transmitted infections. In women, this infection can lead to tubal Infertility. Objective: In this study we investigated C. trachomatis among infertile and fertile women with both polymerase chain reaction (PCR) and ELISA methods in Ahvaz, Iran. Materials and Methods: This case-control study was conducted at the Infertility Clinic of University Jahad, Ahvaz, Iran from January to August 2017. A total of 225 vaginal swabs and blood samples (100 infertile and 125 fertile women) were collected. Detection of C. trachomatis DNA was performed from vaginal swabs by amplification of MOMP gene. Also, anti C. trachomatis immunoglobulin M (IgM) and immunoglobulin G antibodies in the serum samples were recognized by enzyme-linked immunosorbent assay (ELISA). Results: Results showed that, 6 (6%) infertile and 2 (1. 6%) fertile women were positive for IgM (p=0. 21). Also, PCR was positive for C. trachomatis infection in 5 infertile (5%) and 2 fertile women (1. 6%) (p=0. 35). We did not find any seropositive immunoglobulin G in both groups. Conclusion: In this study, no significant difference was found between fertile and infertile groups for C. trachomatis infection. Also, the correlation between IgM and PCR results revealed a relatively strong agreement and seems both PCR and IgM assays are appropriate for the accurate diagnosis of C. trachomatis infections.

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    APA: Copy

    Joolayi, Fatemeh, NAVIDIFAR, TAHEREH, MOHAMMAD JAAFARI, RAZIEH, & AMIN, MANSOUR. (2017). Comparison of Chlamydia trachomatis infection among infertile and fertile women in Ahvaz, Iran: A casecontrol study. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 15(11), 713-718. SID. https://sid.ir/paper/296464/en

    Vancouver: Copy

    Joolayi Fatemeh, NAVIDIFAR TAHEREH, MOHAMMAD JAAFARI RAZIEH, AMIN MANSOUR. Comparison of Chlamydia trachomatis infection among infertile and fertile women in Ahvaz, Iran: A casecontrol study. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2017;15(11):713-718. Available from: https://sid.ir/paper/296464/en

    IEEE: Copy

    Fatemeh Joolayi, TAHEREH NAVIDIFAR, RAZIEH MOHAMMAD JAAFARI, and MANSOUR AMIN, “Comparison of Chlamydia trachomatis infection among infertile and fertile women in Ahvaz, Iran: A casecontrol study,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 15, no. 11, pp. 713–718, 2017, [Online]. Available: https://sid.ir/paper/296464/en

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