Knowledge and attitude toward genetic diseases and genetic tests among pre-marriage individuals: A cross-sectional study in northern Iran

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HASHEMI SOTEH MOHAMMAD BAGHER; Vali Nejad Ali; Ataei Golamreza; TAFAZOLI ALIREZA; Ghasemi Dariush; Siamy Rita

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Journal: International Journal of Reproductive BioMedicine Year:2019 | Volume:17 | Issue:8 Page(s): 543-550

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Title

Knowledge and attitude toward genetic diseases and genetic tests among pre-marriage individuals: A cross-sectional study in northern Iran

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Keywords

Attitude

Knowledge

Genetic testing

Genetic counseling

Prenataldiagnosis

Abstract

Background: Genetic testing has been widely introduced for many hereditary disorders. While the Attitudes towards these facilities have been evaluated in many countries, there are only a few reports on the Knowledge of and the orientation among Iranians. Objective: The current study assesses the Attitudes and Knowledge of pre-marriage individuals toward the availability and use of genetic tests. Materials and Methods: A comprehensive questionnaire was distributed among 408 marrying individuals. The questions addressed the demographic characteristics along the registration of participant’ s Knowledge, education, and Attitude toward Genetic testing. The individuals were divided into three groups based on their Knowledge: 1) Scored above 80 to 100 were defined as “ good” 2) 60 to 80 as “ average” 3) less than 60 as “ poor” Knowledge. Result: Most participants (86%) believed consanguineous marriages increase the risk of genetic diseases; 82. 3% knew that thalassemia is a type of genetic disease, only 33. 3% could distinguish prenatal diagnosis (PND) from other laboratory tests. The relationship between the participants’ Knowledge and their level of education was significant (r = 0. 78, p < 0. 001), age (r =􀀀 0. 16, p < 0. 01), and urbanity (p < 0. 01). A prominent relationship was observed between the Knowledge (r = 0. 64, p < 0. 001) or education (r = 0. 62, p < 0. 001) and people’ s desire to use the genetic tests before the wedding ceremony. No significant correlations were found between the participant’ s Attitude and their ages/urbanity. Most of the individuals agreed to arrange a Genetic counseling before marriage (0. 94%). Conclusion: This study revealed that most individuals were interested in using Genetic counseling services and genetic tests before marriage.

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APA: Copy

HASHEMI SOTEH, MOHAMMAD BAGHER, Vali Nejad, Ali, Ataei, Golamreza, TAFAZOLI, ALIREZA, Ghasemi, Dariush, & Siamy, Rita. (2019). Knowledge and attitude toward genetic diseases and genetic tests among pre-marriage individuals: A cross-sectional study in northern Iran. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 17(8), 543-550. SID. https://sid.ir/paper/296591/en

Vancouver: Copy

HASHEMI SOTEH MOHAMMAD BAGHER, Vali Nejad Ali, Ataei Golamreza, TAFAZOLI ALIREZA, Ghasemi Dariush, Siamy Rita. Knowledge and attitude toward genetic diseases and genetic tests among pre-marriage individuals: A cross-sectional study in northern Iran. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2019;17(8):543-550. Available from: https://sid.ir/paper/296591/en

IEEE: Copy

MOHAMMAD BAGHER HASHEMI SOTEH, Ali Vali Nejad, Golamreza Ataei, ALIREZA TAFAZOLI, Dariush Ghasemi, and Rita Siamy, “Knowledge and attitude toward genetic diseases and genetic tests among pre-marriage individuals: A cross-sectional study in northern Iran,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 17, no. 8, pp. 543–550, 2019, [Online]. Available: https://sid.ir/paper/296591/en

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