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Information Journal Paper

Title

The prevalence of hypovitaminosis D and its risk factors in pregnant women and their newborns in the Middle East: A systematic review

Pages

  685-708

Abstract

 Background: Pregnant women and Newborns are at risk for Vitamin D deficiency (VDD). Also, poor health outcomes for pregnant women with VDD are reported in the published literature. Objective: The aim of this systematic review was to estimate the prevalence of hypovitaminosis D and the associated risk factors for hypovitaminosis D in Middle Eastern pregnant women and their Newborns. Materials and Methods: The international electronic databases PubMed and Scopus for the years 2000-2017 were utilized to identify studies of Vitamin D status for pregnant women and Newborns in the Middle East. Of the 1, 785 reports identified, 1, 734 met exclusion criteria and 51 studies were included for this review. Results: The prevalence of circulating 25-hydroxyVitamin D (25(OH)D) < 50 nmol/L as a marker of Vitamin D status in pregnant women and their Newborns was between 24. 5-98% and 22-100%, respectively. The prevalence of 25(OH) D < 25 nmol/L in pregnant women and their Newborns was over a wide range between 16. 7-80% and 22-82%, respectively. Predictors for low maternal and neonatal 25(OH)D concentrations included decreased Vitamin D synthesis due to reduced exposure to sunlight and decreased nutritional intake of Vitamin D. A predictor of low neonatal 25(OH)D concentrations included maternal Vitamin D status and the correlation between Vitamin D concentrations in maternal and Cord blood. Conclusion: The high prevalence of VDD in the pregnant women of the Middle East underscores the necessity of implementing national prevention and intervention strategies. A clear policy for clinicians and healthcare workers is needed for screening and maintaining sufficient Vitamin D status during Pregnancy.

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    APA: Copy

    HAJIZADEH, SHAYESTEH, Shary, Judy Rankin, Reed, Susan Gayle, & Wagner, Carol Lynn. (2019). The prevalence of hypovitaminosis D and its risk factors in pregnant women and their newborns in the Middle East: A systematic review. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 17(10), 685-708. SID. https://sid.ir/paper/296605/en

    Vancouver: Copy

    HAJIZADEH SHAYESTEH, Shary Judy Rankin, Reed Susan Gayle, Wagner Carol Lynn. The prevalence of hypovitaminosis D and its risk factors in pregnant women and their newborns in the Middle East: A systematic review. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2019;17(10):685-708. Available from: https://sid.ir/paper/296605/en

    IEEE: Copy

    SHAYESTEH HAJIZADEH, Judy Rankin Shary, Susan Gayle Reed, and Carol Lynn Wagner, “The prevalence of hypovitaminosis D and its risk factors in pregnant women and their newborns in the Middle East: A systematic review,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 17, no. 10, pp. 685–708, 2019, [Online]. Available: https://sid.ir/paper/296605/en

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