Comparison of letrozole with gonadotropin-releasing hormone agonist in frozen embryo transfer after recurrent implantation failure: An RCT

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KHADEM GHAEBI NAYEREH; Mahmoudiniya Malihe; NAJAF NAJAFI MONA; Zohdi Elnaz; Attaran Matin

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: International Journal of Reproductive BioMedicine Year:2020 | Volume:18 | Issue:2 Page(s): 105-112

Download Full-Text

View:

188

Download:

107

Cites:

Information Journal Paper

Title

Comparison of letrozole with gonadotropin-releasing hormone agonist in frozen embryo transfer after recurrent implantation failure: An RCT

Author(s)

Keywords

Letrozole

Fertilization in vitro

Pregnancy outcome

Abstract

Background: The use of frozen embryo transfer (FET) is increasing worldwide in the treatment of infertility by in vitro fertilization. Different methods of endometrial preparation for FET have been suggested. Objective: The aim of this study was to compare the Pregnancy outcomes after treatment with Letrozole and those after treatment with the combination of gonadotropin-releasing hormone (GnRH) agonist and estradiol in FET. Materials and Methods: This randomized controlled trial study was conducted on 142 infertile women with a history of previous FET failure. Participants were randomly assigned to two groups (n = 71 each). The GnRH group received 500 μ g of buserelin plus 4mg estradiol (which increased to 8 mg if endometrial thickness was less than 5 mm), and the Letrozole group received 5 mg of Letrozole plus 75 IU of recombinant human follicle-stimulating hormone). At least two high-quality embryos were transferred to each subject in both groups. The outcome measures were clinical pregnancy rate and fetal heart rate detection. Results: Subjects in the study groups had similar demographic characteristics and baseline clinical condition. Mean endometrial thickness in the Letrozole and GnRH agonist groups were 8. 90 ± 0. 88 mm and 8. 99 ± 0. 85 mm, respectively (p = 0. 57). The number of positive results of the beta human chorionic gonadotropin test and detection of fetal heartbeat were not significantly different between the groups (p > 0. 05). Conclusion: The administration of Letrozole and GnRH may produce similar Pregnancy outcomes in FET.

Cites

Comparison of Pregnancy Rate of Frozen Embryos Using Two Methods of long with GnRH Agonist and OCP with Estradiol Only

References

No record.

Cite

APA: Copy

KHADEM GHAEBI, NAYEREH, Mahmoudiniya, Malihe, NAJAF NAJAFI, MONA, Zohdi, Elnaz, & Attaran, Matin. (2020). Comparison of letrozole with gonadotropin-releasing hormone agonist in frozen embryo transfer after recurrent implantation failure: An RCT. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), 18(2), 105-112. SID. https://sid.ir/paper/296637/en

Vancouver: Copy

KHADEM GHAEBI NAYEREH, Mahmoudiniya Malihe, NAJAF NAJAFI MONA, Zohdi Elnaz, Attaran Matin. Comparison of letrozole with gonadotropin-releasing hormone agonist in frozen embryo transfer after recurrent implantation failure: An RCT. INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE)[Internet]. 2020;18(2):105-112. Available from: https://sid.ir/paper/296637/en

IEEE: Copy

NAYEREH KHADEM GHAEBI, Malihe Mahmoudiniya, MONA NAJAF NAJAFI, Elnaz Zohdi, and Matin Attaran, “Comparison of letrozole with gonadotropin-releasing hormone agonist in frozen embryo transfer after recurrent implantation failure: An RCT,” INTERNATIONAL JOURNAL OF REPRODUCTIVE BIOMEDICINE (IRANIAN JOURNAL OF REPRODUCTIVE MEDICINE), vol. 18, no. 2, pp. 105–112, 2020, [Online]. Available: https://sid.ir/paper/296637/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops