Comparison of Pregnancy Rate of Frozen Embryos Using Two Methods of long with GnRH Agonist and OCP with Estradiol Only

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RABIEI SOGHRA; FALLAH MOHAMMAD; JAMSHIDI FATEMEH

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Journal: Avicenna Journal of Clinical Medicine Year:2020 | Volume:27 | Issue:1 (95) Page(s): 5-12

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Title

Comparison of Pregnancy Rate of Frozen Embryos Using Two Methods of long with GnRH Agonist and OCP with Estradiol Only

Author(s)

RABIEI SOGHRA | FALLAH MOHAMMAD | JAMSHIDI FATEMEH | Issue Writer Certificate

Keywords

EstradiolQ1

Frozen EmbryoQ2

GnRH AgonistQ1

Abstract

Background and Objective: The management method of the luteal phase in the treatment of infertility is controversial, and there is no general agreement regarding the preferred protocol. The purpose of this study was to compare the pregnancy rate of Frozen Embryos in the long method with the gonadotropin-releasing hormone (GnRH) agonist and oral contraceptives (OCP) with Estradiol alone. Materials and Methods: In this clinical trial study, a total of 128 in vitro fertilization candidates were randomly assigned into two groups of receiving 64 GnRH-OCP agonists (group A) and Estradiol alone (group B). In group A, 15 days after menses, the patients received OCP for 12 days, and GnRH Agonists were also given for 14 days. In group B, 6-mg Estradiol valerate tablets were used twice a day for 5 days, in case of normal endometrial thickness for at least 10 days. Then, the consequences of the intervention were compared between the two groups. Results: According to the obtained results, the study groups were similar regarding mean age and duration, type, and cause of infertility (P>0. 05), and there was no significant difference in this regard. The mean of taken eggs, formed embryos, and transferred embryos were similar in terms of the number, motility, and morphology of the spermatozoa. The frequency rates of laboratory and clinical pregnancies were 17. 2% and 15. 6% as well as 23. 4% and 20. 3% in groups A and B, respectively (P>0. 05). The rates of abortion and multiple pregnancies were 1. 6% and 3. 1% in groups A and B, respectively (P>0. 05). Conclusion: The pregnancy rates of Frozen Embryos in the long method with GnRH Agonist and OCP with only Estradiol were not reported with a significant difference regarding pregnancy outcomes.

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APA: Copy

RABIEI, SOGHRA, FALLAH, MOHAMMAD, & JAMSHIDI, FATEMEH. (2020). Comparison of Pregnancy Rate of Frozen Embryos Using Two Methods of long with GnRH Agonist and OCP with Estradiol Only. AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES), 27(1 (95) ), 5-12. SID. https://sid.ir/paper/400031/en

Vancouver: Copy

RABIEI SOGHRA, FALLAH MOHAMMAD, JAMSHIDI FATEMEH. Comparison of Pregnancy Rate of Frozen Embryos Using Two Methods of long with GnRH Agonist and OCP with Estradiol Only. AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES)[Internet]. 2020;27(1 (95) ):5-12. Available from: https://sid.ir/paper/400031/en

IEEE: Copy

SOGHRA RABIEI, MOHAMMAD FALLAH, and FATEMEH JAMSHIDI, “Comparison of Pregnancy Rate of Frozen Embryos Using Two Methods of long with GnRH Agonist and OCP with Estradiol Only,” AVICENNA JOURNAL OF CLINICAL MEDICINE (SCIENTIFIC JOURNAL OF HAMADAN UNIVERSITY OF MEDICAL SCIENCES AND HEALTH SERVICES), vol. 27, no. 1 (95) , pp. 5–12, 2020, [Online]. Available: https://sid.ir/paper/400031/en

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