DETECTION OF TOXOPLASMA PARASITEMIA BY PCR: DOES IT CORRELATE WITH IGG AND IGM ANTIBODY TITERS?

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

HAGHPANAH BEHZAD; SALEHI MANSOUR; SADRI SH.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Iranian Journal of Immunology Year:2006 | Volume:3 | Issue:1 Page(s): 47-53

Download Full-Text

View:

354

Download:

149

Cites:

Information Journal Paper

Title

DETECTION OF TOXOPLASMA PARASITEMIA BY PCR: DOES IT CORRELATE WITH IGG AND IGM ANTIBODY TITERS?

Author(s)

HAGHPANAH BEHZAD | SALEHI MANSOUR | SADRI SH. | Issue Writer Certificate

Keywords

TOXOPLASMOSIS

PARASITEMIA

Abstract

Background: TOXOPLASMOSIS is a zeonotic disease with high seroprevalence worldwide. Several immunological methods have been described for diagnosis of TOXOPLASMOSIS. Objective: To determine the PARASITEMIA priod in patients infected with toxoplasma using PCR and comparing serological data with molecular results. Methods: In this study 154 serum samples from patients with TOXOPLASMOSIS were examined. Presence of parasite DNA was evaluated using PCR method. IgG and IgM antibody titers were measured using IFA test. Results: Of 154 studied samples, 28 were positive for IgM and 60 were positive for IgG with titers higher than 1/400. PCR was performed on those samples having either IgG or IgM titers. Samples with IgM titers lower than 1/800 and higher than 1/3200 had no detectable level of parazite DNA. Parsetemia was detected in cases with IgG titer of 1/100 to 1/200. All samples with no detectable IgM and with IgG titers higher than 1/400 were negative when tested by PCR. Conclusion: IgM specific antibody titer between 1/800 and1/3200 represents a window opportunity in treatment of patients with TOXOPLASMOSIS. Absence of parasite"s DNA in patient with higher IgM antibody titer is explained by the effector mechanism of antibody for clearance of the parasite.

Cites

No record.

References

No record.

Cite

APA: Copy

HAGHPANAH, BEHZAD, SALEHI, MANSOUR, & SADRI, SH.. (2006). DETECTION OF TOXOPLASMA PARASITEMIA BY PCR: DOES IT CORRELATE WITH IGG AND IGM ANTIBODY TITERS?. IRANIAN JOURNAL OF IMMUNOLOGY (IJI), 3(1), 47-53. SID. https://sid.ir/paper/296743/en

Vancouver: Copy

HAGHPANAH BEHZAD, SALEHI MANSOUR, SADRI SH.. DETECTION OF TOXOPLASMA PARASITEMIA BY PCR: DOES IT CORRELATE WITH IGG AND IGM ANTIBODY TITERS?. IRANIAN JOURNAL OF IMMUNOLOGY (IJI)[Internet]. 2006;3(1):47-53. Available from: https://sid.ir/paper/296743/en

IEEE: Copy

BEHZAD HAGHPANAH, MANSOUR SALEHI, and SH. SADRI, “DETECTION OF TOXOPLASMA PARASITEMIA BY PCR: DOES IT CORRELATE WITH IGG AND IGM ANTIBODY TITERS?,” IRANIAN JOURNAL OF IMMUNOLOGY (IJI), vol. 3, no. 1, pp. 47–53, 2006, [Online]. Available: https://sid.ir/paper/296743/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops