SEROPREVALENCE OF VARICELLA-ZOSTER VIRUS IN CHILDREN FROM SHIRAZ-IRAN

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MOTAMEDIFAR M.; HADI N.; HANDJANI F.; MEHRBANI D.; SHAHKARAMI M.K.

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Journal Paper

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Journal: Iranian Journal of Immunology Year:2006 | Volume:3 | Issue:1 Page(s): 43-46

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Title

SEROPREVALENCE OF VARICELLA-ZOSTER VIRUS IN CHILDREN FROM SHIRAZ-IRAN

Author(s)

Keywords

SEROPREVALENCE

VZV

SHIRAZ

IRAN

Abstract

Background: Varicella–zoster virus (VZV) causes varicella (chicken-pox) and herpes zoster, usually a mild disease which is diagnosed clinically with few complications. However, in neonates and healthy adults it can have a severe presentation. Herpes zoster results from VZV reactivation later in life. Objective: To estimate the SEROPREVALENCE of VZV in elementary school children aging 6-10 years old in SHIRAZ, IRAN. Methods: A cross-sectional SEROPREVALENCE survey was conducted on 270 healthy subjects. All serum samples were investigated for immunoglobulin G (IgG) antibody against VZV using a commercial enzyme linked immunosorbent assay (ELISA). Results: Among the studied population, 175 (64.8%) had no detectable antibody levels. The overall SEROPREVALENCE rate was 35.2%. A breakdown of seropositivity to VZV according to age was as follows; 10 years-old, 50%,9 years-old, 48.2%, 8 years-old, 27.3%, 7 years-old, 32.1%, and 6 years-old, 13.2%. Conclusion: As VZV susceptibility in the studied age groups was higher than the expected rate, therefore childhood VZV vaccination is recommended in our region.

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APA: Copy

MOTAMEDIFAR, M., HADI, N., HANDJANI, F., MEHRBANI, D., & SHAHKARAMI, M.K.. (2006). SEROPREVALENCE OF VARICELLA-ZOSTER VIRUS IN CHILDREN FROM SHIRAZ-IRAN. IRANIAN JOURNAL OF IMMUNOLOGY (IJI), 3(1), 43-46. SID. https://sid.ir/paper/296744/en

Vancouver: Copy

MOTAMEDIFAR M., HADI N., HANDJANI F., MEHRBANI D., SHAHKARAMI M.K.. SEROPREVALENCE OF VARICELLA-ZOSTER VIRUS IN CHILDREN FROM SHIRAZ-IRAN. IRANIAN JOURNAL OF IMMUNOLOGY (IJI)[Internet]. 2006;3(1):43-46. Available from: https://sid.ir/paper/296744/en

IEEE: Copy

M. MOTAMEDIFAR, N. HADI, F. HANDJANI, D. MEHRBANI, and M.K. SHAHKARAMI, “SEROPREVALENCE OF VARICELLA-ZOSTER VIRUS IN CHILDREN FROM SHIRAZ-IRAN,” IRANIAN JOURNAL OF IMMUNOLOGY (IJI), vol. 3, no. 1, pp. 43–46, 2006, [Online]. Available: https://sid.ir/paper/296744/en

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