AGE SPECIFIC REFERENCE LEVELS OF SERUM PROSTATE-SPECIFIC ANTIGEN, PROSTATE VOLUME AND PROSTATE SPECIFIC ANTIGEN DENSITY IN HEALTHY IRANIAN MEN

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KHEZRI A.A.A.; SHIRAZI MAHDI; AYAT ELAHI S.M.T.; LOTFI MEHRZAD; ASKARIAN M.; ARIAFAR A.; AFRASIABI M.A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF IMMUNOLOGY Year:2009 | Volume:6 | Issue:1 Page(s): 40-48

Download Full-Text

View:

338

Download:

Cites:

Information Journal Paper

Title

AGE SPECIFIC REFERENCE LEVELS OF SERUM PROSTATE-SPECIFIC ANTIGEN, PROSTATE VOLUME AND PROSTATE SPECIFIC ANTIGEN DENSITY IN HEALTHY IRANIAN MEN

Author(s)

Keywords

PROSTATE

PROSTATE-SPECIFIC ANTIGEN

ELISA

Abstract

Background: It is relevant to highlight that there is not a precise and perfect report on either 95 percentile value (upper limit of normal range) or on appropriate reference intervals for serum PSA in Iranian population.Objective: To determine age-specific reference ranges for serum prostate-specific antigen (PSA) concentration and PSA density (PSAD) and prostate volumes in a population of healthy Iranian men.Methods: Nine-hundred and thirteen healthy Iranian men, aged 50-79 years, underwent a detailed clinical evaluation including a digital rectal examination, a serum PSA determination (DRE) and transrectal ultrasound (TRUS). PSA test was performed on 666 of the subjects and TRUS was done on 633 of them. None of the subjects had any evidence of prostate cancer by any one of the three diagnostic tests and had no history of Lower Urinary Tract Symptoms (LUTS). Age specific ranges for PSA levels, PSA density and prostate volume were determined Results: The serum PSA concentration correlated directly with the subjects’ age (r=0.280; p<0.001) and prostatic volume (r=0.327; p<0.001). Also prostatic volume was directly proportional to age (r=0.197; p<0.001).The serum PSA ranges (95th percentile) for each age range in Iranian men were: 0.00-2.61 ng/ml for 50-59 years; 0.00-3.59 ng/ml for 60-69 years; and 0.00-4.83 ng/ml for 70-79 years. The respective prostate volumes were: 14-59, 16-66 and 18-73ml. Also respective PSA densities were: 0.00-0.076, 0.00-0.10 and 0.00-0.14 ng/ml/ml.Conclusion: The present study confirms earlier reports that serum PSA levels and prostate volume and PSAD are age- and race- dependent, so it is appropriate to have age- specific reference ranges for these variables in various communities around the world. This will increase the positive predictive value of PSA estimation in the diagnosis of prostate cancer in different communities.

Multimedia

No record.

Cites

No record.

References

No record.

Cite

APA: Copy

KHEZRI, A.A.A., SHIRAZI, MAHDI, AYAT ELAHI, S.M.T., LOTFI, MEHRZAD, ASKARIAN, M., ARIAFAR, A., & AFRASIABI, M.A.. (2009). AGE SPECIFIC REFERENCE LEVELS OF SERUM PROSTATE-SPECIFIC ANTIGEN, PROSTATE VOLUME AND PROSTATE SPECIFIC ANTIGEN DENSITY IN HEALTHY IRANIAN MEN. IRANIAN JOURNAL OF IMMUNOLOGY (IJI), 6(1), 40-48. SID. https://sid.ir/paper/296835/en

Vancouver: Copy

KHEZRI A.A.A., SHIRAZI MAHDI, AYAT ELAHI S.M.T., LOTFI MEHRZAD, ASKARIAN M., ARIAFAR A., AFRASIABI M.A.. AGE SPECIFIC REFERENCE LEVELS OF SERUM PROSTATE-SPECIFIC ANTIGEN, PROSTATE VOLUME AND PROSTATE SPECIFIC ANTIGEN DENSITY IN HEALTHY IRANIAN MEN. IRANIAN JOURNAL OF IMMUNOLOGY (IJI)[Internet]. 2009;6(1):40-48. Available from: https://sid.ir/paper/296835/en

IEEE: Copy

A.A.A. KHEZRI, MAHDI SHIRAZI, S.M.T. AYAT ELAHI, MEHRZAD LOTFI, M. ASKARIAN, A. ARIAFAR, and M.A. AFRASIABI, “AGE SPECIFIC REFERENCE LEVELS OF SERUM PROSTATE-SPECIFIC ANTIGEN, PROSTATE VOLUME AND PROSTATE SPECIFIC ANTIGEN DENSITY IN HEALTHY IRANIAN MEN,” IRANIAN JOURNAL OF IMMUNOLOGY (IJI), vol. 6, no. 1, pp. 40–48, 2009, [Online]. Available: https://sid.ir/paper/296835/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops