Effect of cinnamon and turmeric aqueous extracts on serum interleukin-17F level of high fructose-fed rats

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SOHRABI MARYAM; Alahgholi Hajibehzad Mahdi; Gholami Mahmoodian Zahra; Hosseini Siyar Sayed Ali; ZAMANI ALIREZA

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Journal Paper

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Journal: Iranian Journal of Immunology Year:2018 | Volume:15 | Issue:1 Page(s): 38-46

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Title

Effect of cinnamon and turmeric aqueous extracts on serum interleukin-17F level of high fructose-fed rats

Author(s)

Keywords

Cinnamon

Fructose

Interleukin-17

Inflammation

Overweight

Turmeric

Abstract

Background: Studies have indicated that extraweight and obesity induce chronic Inflammation, which can lead to other diseases such as cancers. Objective: To evaluate the effects of two weight-lowering and anti-inflammatory agents including Cinnamon, and Turmeric, on serum levels of Interleukin-17 (IL-17) as a pro-inflammatory cytokine. Methods: In this study, 64 rats were designated in eight groups. The control group received normal diet. The other groups were fed with normal diet plus high Cinnamon (3 mg/ml), high Turmeric (3 mg/ml), high-Fructose solution (30%), Fructose solution with low (0. 15 mg/ml) and high doses (3 mg/ml) of Cinnamon and Turmeric three times per week. The serum level of IL-17F was measured by enzyme-linked immunosorbent assay (ELISA). Results: High Fructose consumption led to an increase in the weight and serum level of IL-17. While, feeding with Cinnamon and Turmeric caused to decline weight but, surprisingly increased IL-17F levels. Conclusion: Although, some studies have showed that Cinnamon and Turmeric supplementation decreased IL-17F under the standard diet, in the presence of high Fructose diet and extraweight their effects were reversed and caused an increase in serum level of IL-17F.

Cites

Antidepressant Effect of Cinnamon (Cinnamomum zeylanicum L. ) Water Extract (CWE) Evaluated by Forced Swimming Test in Mice

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APA: Copy

SOHRABI, MARYAM, Alahgholi Hajibehzad, Mahdi, Gholami Mahmoodian, Zahra, Hosseini Siyar, Sayed Ali, & ZAMANI, ALIREZA. (2018). Effect of cinnamon and turmeric aqueous extracts on serum interleukin-17F level of high fructose-fed rats. IRANIAN JOURNAL OF IMMUNOLOGY (IJI), 15(1), 38-46. SID. https://sid.ir/paper/296912/en

Vancouver: Copy

SOHRABI MARYAM, Alahgholi Hajibehzad Mahdi, Gholami Mahmoodian Zahra, Hosseini Siyar Sayed Ali, ZAMANI ALIREZA. Effect of cinnamon and turmeric aqueous extracts on serum interleukin-17F level of high fructose-fed rats. IRANIAN JOURNAL OF IMMUNOLOGY (IJI)[Internet]. 2018;15(1):38-46. Available from: https://sid.ir/paper/296912/en

IEEE: Copy

MARYAM SOHRABI, Mahdi Alahgholi Hajibehzad, Zahra Gholami Mahmoodian, Sayed Ali Hosseini Siyar, and ALIREZA ZAMANI, “Effect of cinnamon and turmeric aqueous extracts on serum interleukin-17F level of high fructose-fed rats,” IRANIAN JOURNAL OF IMMUNOLOGY (IJI), vol. 15, no. 1, pp. 38–46, 2018, [Online]. Available: https://sid.ir/paper/296912/en

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