Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

333
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

156
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

HYPOLIPIDEMIC ACTIVITY OF GINKGO BILOBA EXTRACT,EGB 761 IN HYPERCHOLESTEROLEMLC WISTAR RATS

Pages

  9-12

Abstract

 CARDIOVASCULAR DISEASES are becoming an increasing problem worldwide. Hypercholesterolemia has been implicated in causation of coronary heart disease. Oxidation of low density lipoprotein has been shown to be prevented by standardized Ginkgo biloba extract, EGb 761. Studies on the effect of Ginkgo biloba on serum lipid levels are lacking. Hence the present study was carried out to study the effect of EGb 761 on serum lipids in female wistar rats. The hypolipidemic effect was compared with a standard dose of lovastatin. The rats were divided into six groups of ten an1malseach. The first group was the normal control. The second group was given cholesterol (400 mg/kg) for 30 days. The third, fourth and fifth groups were given cholesterol and EGb 761 in the doses of 25 mg/kg, 50 mg/kg and 100 mg/kg respectively. The sixth group was given lovastatin (7.2 mg/kg) in addition to cholesterol. SERUM CHOLESTEROL, triglycerides and high density lipoproteins were measured on days 0, 15 and 30. Serum levels on days 15 and 30 were compared using students paired t-test (p < 0.05). There was a significant decrease in SERUM CHOLESTEROL in both the lovastatin and the EGb 761 treated groups. EGb 761 did not produce a significant change in serum triglyceride and high density lipoprotein levels. The animal model used had limitations and further studies are required.

Cites

  • No record.

    • References

    Cite

    APA: Copy

    KUMAR DUBEY, A., KUTTY, G., PATHIYIL SHANKAR, R., & DEVI, A.. (2005). HYPOLIPIDEMIC ACTIVITY OF GINKGO BILOBA EXTRACT,EGB 761 IN HYPERCHOLESTEROLEMLC WISTAR RATS. IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT), 4(1), 9-12. SID. https://sid.ir/paper/297071/en

    Vancouver: Copy

    KUMAR DUBEY A., KUTTY G., PATHIYIL SHANKAR R., DEVI A.. HYPOLIPIDEMIC ACTIVITY OF GINKGO BILOBA EXTRACT,EGB 761 IN HYPERCHOLESTEROLEMLC WISTAR RATS. IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT)[Internet]. 2005;4(1):9-12. Available from: https://sid.ir/paper/297071/en

    IEEE: Copy

    A. KUMAR DUBEY, G. KUTTY, R. PATHIYIL SHANKAR, and A. DEVI, “HYPOLIPIDEMIC ACTIVITY OF GINKGO BILOBA EXTRACT,EGB 761 IN HYPERCHOLESTEROLEMLC WISTAR RATS,” IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT), vol. 4, no. 1, pp. 9–12, 2005, [Online]. Available: https://sid.ir/paper/297071/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top