Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

290
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

0
Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

EFFECT OF CHROMATOGRAPHIC FRACTIONS OF ETHANOLIC EXTRACT OF CROTALARIA JUNCEA (L.) SEEDS ON OVARIAN FOLLICULAR KINETICS AND ESTROUS CYCLE IN ALBINO RATS

Pages

  159-163

Abstract

 In spite of considerable development in contraceptive technology, search for female ANTIFERTILITY agent in plants continues to be a potential area of investigation. The ethanol extract of CROTALARIA JUNCEA seeds which showed promising ANTIOVULATORY activity in female albino RATs was examined for the isolation of its active fractions. Two fractions were obtained using Thin Layer Chromatography (TLC) of the extract. Both fractions were subjected for testing their anti-ovulation activity and ESTROUS CYCLE in RATs. After preliminary trials, the fraction I (200mg/kg body weights) showed maximum ANTIOVULATORY activity when administered orally to the RATs for 30 days. Decreased number of healthy follicles (Class I - ClassVI) and corpora lutea and increased number of regressing follicles (Stage IA, Stage IB, Stage IIA, Stage IIB) were observed in the ovary after 30 days treatment. The treatment caused an increase in the cholesterol level and acid/alkaline phosphatase activity and a decrease in protein and glycogen contents of the ovary. ESTROUS CYCLE was affected as a significant increase in estrus and metaestrus phases and a decrease in diestrus and proestrus phases in the treated groups during experimental period of 30 days were observed. These results suggest that a fraction of ethanolic extract of CROTALARIA JUNCEA might be used as a contraceptive in the females.

Cites

  • No record.

    • References

    Cite

    APA: Copy

    MALASHETTY, V.B., & PATIL, S.B.. (2007). EFFECT OF CHROMATOGRAPHIC FRACTIONS OF ETHANOLIC EXTRACT OF CROTALARIA JUNCEA (L.) SEEDS ON OVARIAN FOLLICULAR KINETICS AND ESTROUS CYCLE IN ALBINO RATS. IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT), 6(2), 159-163. SID. https://sid.ir/paper/297155/en

    Vancouver: Copy

    MALASHETTY V.B., PATIL S.B.. EFFECT OF CHROMATOGRAPHIC FRACTIONS OF ETHANOLIC EXTRACT OF CROTALARIA JUNCEA (L.) SEEDS ON OVARIAN FOLLICULAR KINETICS AND ESTROUS CYCLE IN ALBINO RATS. IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT)[Internet]. 2007;6(2):159-163. Available from: https://sid.ir/paper/297155/en

    IEEE: Copy

    V.B. MALASHETTY, and S.B. PATIL, “EFFECT OF CHROMATOGRAPHIC FRACTIONS OF ETHANOLIC EXTRACT OF CROTALARIA JUNCEA (L.) SEEDS ON OVARIAN FOLLICULAR KINETICS AND ESTROUS CYCLE IN ALBINO RATS,” IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT), vol. 6, no. 2, pp. 159–163, 2007, [Online]. Available: https://sid.ir/paper/297155/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    مرکز اطلاعات علمی SID
    strs
    دانشگاه امام حسین
    بنیاد ملی بازیهای رایانه ای
    کلید پژوه
    ایران سرچ
    ایران سرچ
    File Not Exists.
    Move to top