IN VIVO AND IN VITRO STUDIES ON NEUTRALIZING EFFECTS OF ACORUS CALAMUS AND WITHANIA SOMNIFERA ROOT EXTRACTS AGAINST ECHIS CARINATUS VENOM

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MEENATCHISUNDARAM S.; SINDHU M.K.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT) Year:2011 | Volume:10 | Issue:1 Page(s): 26-30

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Information Journal Paper

Title

IN VIVO AND IN VITRO STUDIES ON NEUTRALIZING EFFECTS OF ACORUS CALAMUS AND WITHANIA SOMNIFERA ROOT EXTRACTS AGAINST ECHIS CARINATUS VENOM

Author(s)

MEENATCHISUNDARAM S. | SINDHU M.K. | Issue Writer Certificate

Keywords

ECHIS CARINATUS VENOMS

ACORUS CALAMUS

WITHANIA SOMNIFERA

PLANT EXTRACTS

LETHALITY

PLA2

Abstract

Neutralization effects of ACORUS CALAMUS and WITHANIA SOMNIFERA root extracts were tested against Echis carinatus venom. Both PLANT EXTRACTS were effectively neutralized the various pharmacological activities induced by Echis carinatus venom. About 0.14 mg of ACORUS CALAMUS and 0.16 mg of WITHANIA SOMNIFERA root extracts were able to completely neutralize the lethal activity of 2LD50 of Echis carinatus venom. Various pharmacological activities like haemorrhagic, coagulant, edema and phospholipase activities were effectively neutralized by both PLANT EXTRACTS. The above observations confirmed that both PLANT EXTRACTS possess potent snake venom neutralizing compounds, which inhibit the activity of ECHIS CARINATUS VENOMS.

Cites

COMPARATIVE STUDY OF ESSENTIAL OIL COMPOSITION OF THE AERIAL PARTS OF THREE POPULATIONS OF ACORUS CALAMUS IN IRAN

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APA: Copy

MEENATCHISUNDARAM, S., & SINDHU, M.K.. (2011). IN VIVO AND IN VITRO STUDIES ON NEUTRALIZING EFFECTS OF ACORUS CALAMUS AND WITHANIA SOMNIFERA ROOT EXTRACTS AGAINST ECHIS CARINATUS VENOM. IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT), 10(1), 26-30. SID. https://sid.ir/paper/297230/en

Vancouver: Copy

MEENATCHISUNDARAM S., SINDHU M.K.. IN VIVO AND IN VITRO STUDIES ON NEUTRALIZING EFFECTS OF ACORUS CALAMUS AND WITHANIA SOMNIFERA ROOT EXTRACTS AGAINST ECHIS CARINATUS VENOM. IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT)[Internet]. 2011;10(1):26-30. Available from: https://sid.ir/paper/297230/en

IEEE: Copy

S. MEENATCHISUNDARAM, and M.K. SINDHU, “IN VIVO AND IN VITRO STUDIES ON NEUTRALIZING EFFECTS OF ACORUS CALAMUS AND WITHANIA SOMNIFERA ROOT EXTRACTS AGAINST ECHIS CARINATUS VENOM,” IRANIAN JOURNAL OF PHARMACOLOGY AND THERAPEUTICS (IJPT), vol. 10, no. 1, pp. 26–30, 2011, [Online]. Available: https://sid.ir/paper/297230/en

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