AN UPDATE ON PLANT DERIVED ANTI-ANDROGENS

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GRANT PAUL; RAMASAMY SHAMIN

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Journal Paper

Paper Information

Journal: International Journal of Endocrinology and Metabolism Year:2012 | Volume:10 | Issue:2 Page(s): 497-502

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Information Journal Paper

Title

AN UPDATE ON PLANT DERIVED ANTI-ANDROGENS

Author(s)

GRANT PAUL | RAMASAMY SHAMIN | Issue Writer Certificate

Keywords

ANDROGENS

ANTI-ANDROGENS

PROSTATE CANCER

PROSTATIC HYPERPLASIA

SPEARMINT

Abstract

Anti-ANDROGENS are an assorted group of drugs and compounds that reduce the levels or activity of androgen hormones within the human body. Disease states in which this is relevant include polycystic ovarian syndrome, hirsutism, acne, benign PROSTATIC HYPERPLASIA, and endocrine related cancers such as carcinoma of the prostate. We provide an overview and discussion of the use of anti-androgen medications in clinical practice and explore the increasing recognition of the benefits of plant-derived anti- ANDROGENS, forexample, SPEARMINT tea in the management of PCOS, for which some evidence about efficacy is beginning to emerge. Other agents covered include red reishi, which has been shown to reduce levels 5-alpha reductase, the enzyme that facilitates conversion of testosterone to dihydrotestosterone (DHT); licorice, which has phytoestrogen effects and reduces testosterone levels; Chinese peony, which promotes the aromatization of testosterone into estrogen; green tea, which contains epigallocatechins and also inhibits 5-alpha reductase, thereby reducing the conversion of normal testosterone into the more potent DHT; black cohosh, which has been shown to kill both androgenresponsive and non-responsive human PROSTATE CANCER cells; chaste tree, which has a reduces prolactin from the anterior pituitary; and saw palmetto extract, which is used as an anti-androgen although it shown no difference in comparison to placebo in clinical trials.

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APA: Copy

GRANT, PAUL, & RAMASAMY, SHAMIN. (2012). AN UPDATE ON PLANT DERIVED ANTI-ANDROGENS. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), 10(2), 497-502. SID. https://sid.ir/paper/297434/en

Vancouver: Copy

GRANT PAUL, RAMASAMY SHAMIN. AN UPDATE ON PLANT DERIVED ANTI-ANDROGENS. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM)[Internet]. 2012;10(2):497-502. Available from: https://sid.ir/paper/297434/en

IEEE: Copy

PAUL GRANT, and SHAMIN RAMASAMY, “AN UPDATE ON PLANT DERIVED ANTI-ANDROGENS,” INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM (IJEM), vol. 10, no. 2, pp. 497–502, 2012, [Online]. Available: https://sid.ir/paper/297434/en

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