A Model for Induction of Dysplasia in Hamster Mucosal Pouch

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POURSHAHIDI SARA; Ghasemzadeh Hoseini Elaheh; EBRAHIMI HOOMAN; ALAEDDINI MOJGAN; ETEMAD MOGHADAM SHAHROO; SHIRAZIAN SHIVA

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Journal Paper

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Journal: Frontiers in Dentistry Year:2019 | Volume:16 | Issue:5 Page(s): 402-406

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Title

A Model for Induction of Dysplasia in Hamster Mucosal Pouch

Author(s)

Keywords

Precancerous Conditions;7

12-dimethylbenz(a)anthracene;Administration

Mucosal

Abstract

Induction of premalignant lesions in animal models is of high value for research purposes. This study aimed to induce dysplasia in hamster Mucosal pouch for investigation of dysplastic lesions using dimethylbenz(a)anthracene. The buccal pouch of 10 hamsters was painted with dimethylbenz(a)anthracene for 10 weeks every other day. At 5 and 10 weeks, they underwent histopathological analysis. Clinically, there was no change until week 7; after which Mucosal thickening occurred. Hamsters scarified at 5 weeks and 10 weeks demonstrated mild and moderate dysplasia, respectively. dimethylbenz(a)anthracene is a useful tool for inducing dysplastic lesions in the buccal pouch mucosa of hamsters.

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APA: Copy

POURSHAHIDI, SARA, Ghasemzadeh Hoseini, Elaheh, EBRAHIMI, HOOMAN, ALAEDDINI, MOJGAN, ETEMAD MOGHADAM, SHAHROO, & SHIRAZIAN, SHIVA. (2019). A Model for Induction of Dysplasia in Hamster Mucosal Pouch. FRONTIERS IN DENTISTRY (JOURNAL OF DENTISTRY OF TEHRAN UNIVERSITY OF MEDICAL SCIENCES), 16(5), 402-406. SID. https://sid.ir/paper/298168/en

Vancouver: Copy

POURSHAHIDI SARA, Ghasemzadeh Hoseini Elaheh, EBRAHIMI HOOMAN, ALAEDDINI MOJGAN, ETEMAD MOGHADAM SHAHROO, SHIRAZIAN SHIVA. A Model for Induction of Dysplasia in Hamster Mucosal Pouch. FRONTIERS IN DENTISTRY (JOURNAL OF DENTISTRY OF TEHRAN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2019;16(5):402-406. Available from: https://sid.ir/paper/298168/en

IEEE: Copy

SARA POURSHAHIDI, Elaheh Ghasemzadeh Hoseini, HOOMAN EBRAHIMI, MOJGAN ALAEDDINI, SHAHROO ETEMAD MOGHADAM, and SHIVA SHIRAZIAN, “A Model for Induction of Dysplasia in Hamster Mucosal Pouch,” FRONTIERS IN DENTISTRY (JOURNAL OF DENTISTRY OF TEHRAN UNIVERSITY OF MEDICAL SCIENCES), vol. 16, no. 5, pp. 402–406, 2019, [Online]. Available: https://sid.ir/paper/298168/en

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