LEFT VENTRICULAR FUNCTION AFTER ARTERIAL SWITCH OPERATION AS ASSESSED BY TWO-DIMENSIONAL SPECKLE-TRACKING ECHOCARDIOGRAPHY IN PATIENTS WITH SIMPLE TRANSPOSITION OF THE GREAT ARTERIES

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MALAKAN RAD ELAHEH; GHANDI YAZDAN; KOCHARIAN ARMEN; MIRZAAGHAYAN MOHAMMADREZA

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Paper Information

Journal: THE JOURNAL OF TEHRAN UNIVERSITY HEART CENTER Year:2016 | Volume:11 | Issue:3 Page(s): 105-110

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Title

LEFT VENTRICULAR FUNCTION AFTER ARTERIAL SWITCH OPERATION AS ASSESSED BY TWO-DIMENSIONAL SPECKLE-TRACKING ECHOCARDIOGRAPHY IN PATIENTS WITH SIMPLE TRANSPOSITION OF THE GREAT ARTERIES

Author(s)

MALAKAN RAD ELAHEH | GHANDI YAZDAN | KOCHARIAN ARMEN | MIRZAAGHAYAN MOHAMMADREZA | Issue Writer Certificate

Keywords

ARTERIAL SWITCH OPERATION

ECHOCARDIOGRAPHY

TRANSPOSITION OF GREAT VESSELS

Abstract

Background: The late postoperative course for children with transposition of the great arteries (TGA) with an intact ventricular septum (IVS) is very important because the coronary arteries may be at risk of damage during ARTERIAL SWITCH OPERATION (ASO). We sought to investigate left ventricular function in patients with TGA/IVS by ECHOCARDIOGRAPHY.Methods: From March 2011 to December 2012, totally 20 infants (12 males and 8 females) with TGA/IVS were evaluated via 2-dimensional speckle-tracking ECHOCARDIOGRAPHY (2D STE) more than 6 months after they underwent ASO. A control group of age-matched infants and children was also studied. Left ventricular longitudinal strain (S), strain rate (SR), time to peak systolic longitudinal strain (TPS), and time to peak systolic longitudinal strain rate (TPSR) were measured and compared between the 2 groups.Results: Mean±SD of age at the time of study in the patients with TGA/IVS was 15±5 months, and also age at the time of ASO was 12±3 days. Weight was 3.13±0.07 kg at birth and 8.83±1.57 kg at the time of ASO. Global strain (S), Time to peak strain rate (TPSR), and Time to peak strain (TPS) were not significantly different between the 2 groups, whereas global strain rate (SR) was significantly different (p value<0.001). In the 3-chamber view, the values of S in the lateral, septal, inferior, and anteroseptal walls were significantly different between the 2 groups (p value<0.001), and SR in the posterior wall was significantly different between the 2 groups (p value<0.001). There were no positive correlations between S and SR in terms of the variables of heart rate, total cardiopulmonary bypass time, and aortic cross-clamp time. There were no statistically significant differences between the 2 groups regarding S, SR, TPS, and TPSR in the anteroseptal and posterior walls in the 3-chamber view and in the lateral and septal walls in the 4-chamber view.Conclusion: We showed that between 6 and 18 months after a successful ASO, the parameters of S, SR, and global TPS were normal in our patients with TGA/IVS. However, LV myocardial TPSR did not normalize in this time period.

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APA: Copy

MALAKAN RAD, ELAHEH, GHANDI, YAZDAN, KOCHARIAN, ARMEN, & MIRZAAGHAYAN, MOHAMMADREZA. (2016). LEFT VENTRICULAR FUNCTION AFTER ARTERIAL SWITCH OPERATION AS ASSESSED BY TWO-DIMENSIONAL SPECKLE-TRACKING ECHOCARDIOGRAPHY IN PATIENTS WITH SIMPLE TRANSPOSITION OF THE GREAT ARTERIES. THE JOURNAL OF TEHRAN UNIVERSITY HEART CENTER, 11(3), 105-110. SID. https://sid.ir/paper/302078/en

Vancouver: Copy

MALAKAN RAD ELAHEH, GHANDI YAZDAN, KOCHARIAN ARMEN, MIRZAAGHAYAN MOHAMMADREZA. LEFT VENTRICULAR FUNCTION AFTER ARTERIAL SWITCH OPERATION AS ASSESSED BY TWO-DIMENSIONAL SPECKLE-TRACKING ECHOCARDIOGRAPHY IN PATIENTS WITH SIMPLE TRANSPOSITION OF THE GREAT ARTERIES. THE JOURNAL OF TEHRAN UNIVERSITY HEART CENTER[Internet]. 2016;11(3):105-110. Available from: https://sid.ir/paper/302078/en

IEEE: Copy

ELAHEH MALAKAN RAD, YAZDAN GHANDI, ARMEN KOCHARIAN, and MOHAMMADREZA MIRZAAGHAYAN, “LEFT VENTRICULAR FUNCTION AFTER ARTERIAL SWITCH OPERATION AS ASSESSED BY TWO-DIMENSIONAL SPECKLE-TRACKING ECHOCARDIOGRAPHY IN PATIENTS WITH SIMPLE TRANSPOSITION OF THE GREAT ARTERIES,” THE JOURNAL OF TEHRAN UNIVERSITY HEART CENTER, vol. 11, no. 3, pp. 105–110, 2016, [Online]. Available: https://sid.ir/paper/302078/en

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