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Information Journal Paper

Title

CHILDHOOD GUILLIAN-BARRE SYNDROME IN THEIRAN'S EAST AZERBAIJAN PROVINCE: 2001-2005

Pages

  25-31

Abstract

 Objective: This study aims at determining the epidemiologic, presenting symptoms, clinical course and electrophysiologic features of CHILDHOOD Guillain-Barre Syndrome (GBS) in the EAST AZARBAIJAN province over a period of five years.Materials & Methods: All the patients, aged< 15 years, referred/admitted to Tabriz Children Hospital with GBS between January 2001 and December 2005 were investigated.Results: One hundred and twelve subjects were enrolled during this period. The average annual incidence rate was 2.21 per 100000 population of children aged<15 years (CI 95%: 1.8-2.6); the highest proportion of 29% was observed in winter (P=0.10); mean age (SO) of subjects was 5.1 (3.3) years, while 61.6% were£5 years. The male / female ratio was 1.3. Antecedent events were identified in 80 (71.4%) patients. The most common manifestation was limb weakness; at the peak of the disease course, only 8 (7.1%) patients were able to walk without assistance. Cranial nerve involvement was found in 37.5%. Fifteen percent of patients had autonomic dysfunction, and 32.2% complained of neuropathic pain. Artificial ventilation was needed in 10.7% of patients, and three patients (2.7%) died due to cardiac arrest. Electrophysiological examination showed the demyelinating type of the disease in 54.5%; axonal type in 35.7% and 9.8% as unclassified or normal pattern. Short time to reach nadir (P=0.008), cranial nerve involvement (P=0.000) autonomic involvement (P=0.001), and axonal pattern on electro diagnosis (P=0.043) were found as risk factors for respiratory failure.In follow-up, at the end of one year, 95% of patients could walk without aid.Conclusion: The axonal type of GBS is a relatively common form of CHILDHOOD GBS occurring in East Azerbaijan.

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    APA: Copy

    BARZEGAR, M., DAVARI FARID, S., SHIRINZADEH DASTGIRI, S., MALEKIAN, ARMEN, & TOUPCHIZADEH, VAHIDEH. (2008). CHILDHOOD GUILLIAN-BARRE SYNDROME IN THEIRAN'S EAST AZERBAIJAN PROVINCE: 2001-2005. IRANIAN JOURNAL OF CHILD NEUROLOGY (IJCN), 2(4), 25-31. SID. https://sid.ir/paper/303214/en

    Vancouver: Copy

    BARZEGAR M., DAVARI FARID S., SHIRINZADEH DASTGIRI S., MALEKIAN ARMEN, TOUPCHIZADEH VAHIDEH. CHILDHOOD GUILLIAN-BARRE SYNDROME IN THEIRAN'S EAST AZERBAIJAN PROVINCE: 2001-2005. IRANIAN JOURNAL OF CHILD NEUROLOGY (IJCN)[Internet]. 2008;2(4):25-31. Available from: https://sid.ir/paper/303214/en

    IEEE: Copy

    M. BARZEGAR, S. DAVARI FARID, S. SHIRINZADEH DASTGIRI, ARMEN MALEKIAN, and VAHIDEH TOUPCHIZADEH, “CHILDHOOD GUILLIAN-BARRE SYNDROME IN THEIRAN'S EAST AZERBAIJAN PROVINCE: 2001-2005,” IRANIAN JOURNAL OF CHILD NEUROLOGY (IJCN), vol. 2, no. 4, pp. 25–31, 2008, [Online]. Available: https://sid.ir/paper/303214/en

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