EFFECTS OF GROWTH HORMONE ON MUSCLE STRENGTH, TONE AND MOBILITY OF CHILDREN WITH PRADER-WILLI SYNDROME

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SALEHPOUR SHADAB; ROHANI FARZANEH; ARYANI OMID; HOUSHMAND MASSOUD; HASHEMINEZHAD FARHAD; REZVANI KASHANI MORTEZA; MAHVELATI SHAMSABADI FARHAD; POURNASIRI ZAHRA

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Journal: Iranian Journal of Child Neurology Year:2011 | Volume:5 | Issue:1 Page(s): 29-33

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Title

EFFECTS OF GROWTH HORMONE ON MUSCLE STRENGTH, TONE AND MOBILITY OF CHILDREN WITH PRADER-WILLI SYNDROME

Author(s)

Keywords

PREDER-WILLI SYNDROME

PWS

GROWTH HORMONE

AGILITY

STRENGTH

Abstract

Objective: Prader-Willi Syndrome (PWS) is a genetic syndrome presenting with severe hypotonia and decreased AGILITY. GROWTH HORMONE (GH), which is often used in these patients to treat short stature and obesity, seems improve hypotonia, physical STRENGTH, activity, and locomotor developmental ability. The aim of this study was to find the effects of GROWTH HORMONE on AGILITY and STRENGTH of these patients.Material & Methods: In a prospective randomized controlled clinical trial in an out-patient pediatric endocrine clinic in Tehran, 21 PWS children (12 boys and 9 girls, 4 to 9 years old) were divided into either GH-treated or control groups and followed for two years. AGILITY run, sit ups, weight lifting, and inspiratory and expiratory STRENGTH were considered as the main outcome measures.Results: All the outcome measures of the GH treated group showed a significant improvement compared to the control group.Conclusion: GH causes a significant improvement in AGILITY and STRENGTH of PWS children.

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APA: Copy

SALEHPOUR, SHADAB, ROHANI, FARZANEH, ARYANI, OMID, HOUSHMAND, MASSOUD, HASHEMINEZHAD, FARHAD, REZVANI KASHANI, MORTEZA, MAHVELATI SHAMSABADI, FARHAD, & POURNASIRI, ZAHRA. (2011). EFFECTS OF GROWTH HORMONE ON MUSCLE STRENGTH, TONE AND MOBILITY OF CHILDREN WITH PRADER-WILLI SYNDROME. IRANIAN JOURNAL OF CHILD NEUROLOGY (IJCN), 5(1), 29-33. SID. https://sid.ir/paper/303293/en

Vancouver: Copy

SALEHPOUR SHADAB, ROHANI FARZANEH, ARYANI OMID, HOUSHMAND MASSOUD, HASHEMINEZHAD FARHAD, REZVANI KASHANI MORTEZA, MAHVELATI SHAMSABADI FARHAD, POURNASIRI ZAHRA. EFFECTS OF GROWTH HORMONE ON MUSCLE STRENGTH, TONE AND MOBILITY OF CHILDREN WITH PRADER-WILLI SYNDROME. IRANIAN JOURNAL OF CHILD NEUROLOGY (IJCN)[Internet]. 2011;5(1):29-33. Available from: https://sid.ir/paper/303293/en

IEEE: Copy

SHADAB SALEHPOUR, FARZANEH ROHANI, OMID ARYANI, MASSOUD HOUSHMAND, FARHAD HASHEMINEZHAD, MORTEZA REZVANI KASHANI, FARHAD MAHVELATI SHAMSABADI, and ZAHRA POURNASIRI, “EFFECTS OF GROWTH HORMONE ON MUSCLE STRENGTH, TONE AND MOBILITY OF CHILDREN WITH PRADER-WILLI SYNDROME,” IRANIAN JOURNAL OF CHILD NEUROLOGY (IJCN), vol. 5, no. 1, pp. 29–33, 2011, [Online]. Available: https://sid.ir/paper/303293/en

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