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Information Journal Paper

Title

ZINC STATUS IN FEBRILE SEIZURE: A CASE-CONTROL STUDY

Pages

  20-23

Abstract

 Objective FEBRILE seizure is the most common type of seizure in children. Their incidence is 2-5%. There are different hypotheses about relationship between neurotransmitters and trace elements (such as zinc) and FEBRILE seizure. Zinc, as a major element of some enzymes, plays an important role in the central nervous system (CNS) and can affect some inhibitory mechanisms of CNS. The aim of the present study was to determine whether there were any changes in serum zinc level in children with FEBRILE seizure in comparison with FEBRILE children without seizure.Materials&Methods this case-control study was performed on 100 patients aged 6 months to 6 years. This study was conducted between January and August 2012, on 50 children with FEBRILE SEIZURES (case) and 50 FEBRILE children without SEIZURES (control), that were referred to Amirkola Children Hospital (a referral hospital in the north of Iran). Two groups were matched for age and sex. The serum zinc levels in the both groups were determined by atomic absorption spectrophotometry method.Results the mean serum zinc level was 0.585±0.166 mg/L and 0.704±0.179 mg/L in the case group and the control group, respectively (p=0.001). The mean serum zinc level was significantly lower in the FEBRILE seizure group compared to the control groups.Conclusion our findings revealed that serum zinc level was significantly lower in children with simple FEBRILE seizure in comparison with FEBRILE children without seizure. It can emphasize the hypothesis that there is a relation between serum zinc level and FEBRILE seizure in children.

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    • Cite

    APA: Copy

    SALEHIOMRAN, MOHAMMAD REZA, & MAHZARI, MASOUMEH. (2013). ZINC STATUS IN FEBRILE SEIZURE: A CASE-CONTROL STUDY. IRANIAN JOURNAL OF CHILD NEUROLOGY (IJCN), 7(4), 20-23. SID. https://sid.ir/paper/303387/en

    Vancouver: Copy

    SALEHIOMRAN MOHAMMAD REZA, MAHZARI MASOUMEH. ZINC STATUS IN FEBRILE SEIZURE: A CASE-CONTROL STUDY. IRANIAN JOURNAL OF CHILD NEUROLOGY (IJCN)[Internet]. 2013;7(4):20-23. Available from: https://sid.ir/paper/303387/en

    IEEE: Copy

    MOHAMMAD REZA SALEHIOMRAN, and MASOUMEH MAHZARI, “ZINC STATUS IN FEBRILE SEIZURE: A CASE-CONTROL STUDY,” IRANIAN JOURNAL OF CHILD NEUROLOGY (IJCN), vol. 7, no. 4, pp. 20–23, 2013, [Online]. Available: https://sid.ir/paper/303387/en

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