مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

video

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

sound

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Persian Version

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

View:

411
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Download:

176
مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Cites:

Information Journal Paper

Title

ANTI-COAGULATION DURING PREGNANCY IN WOMEN WITH MECHANICAL HEART VALVES: A PROSPECTIVE STUDY

Pages

  47-51

Abstract

 Background: PREGNANCY is associated with a hypercoagulable state, therefore the optimal ANTICOAGULANTs for potential use in pregnant women with prosthetic heart valves are controversial.The aim of this study is to investigate the effect of ANTICOAGULANTs on PREGNANCY outcomes and their potential risks in pregnant women with MECHANICAL HEART VALVEs.Materials and Methods: In this prospective cohort study, we followed 44 women with 49 pregnancies who had MECHANICAL HEART VALVEs from September 2002 to September 2007. A total of 38 patients took WARFARIN throughout their pregnancies (group A). In 11 patients, WARFARIN was changed to HEPARIN during the first trimester and then again to WARFARIN during 12th to 36th weeks of gestational age (group B). All women took WARFARIN from 36th weeks of gestational age until delivery.Results: In group A, there were 22 live births (57.9%), 15 abortions (39.5%) and 1 maternal death (2.6%). In group B, there were seven live births (63.6%), three spontaneous abortions (27.3%) and one intra-uterine fetal death (9.1%). There was no significant difference in live birth rate between the two groups (p=0.24). Thirty-three pregnancies (86.8%) in group A and five pregnancies (45.4%) in group B had no maternal complications (p=0.004). The difference in PREGNANCY complications between both groups was significant (p<0.001) Conclusion: The present study shows that low dose WARFARIN (5 mg/day or less) may be safe during the first trimester of PREGNANCY. Maternal adverse events are low when pregnant women with MECHANICAL HEART VALVEs remain on a WARFARIN regimen. The risk of embryopathy does not necessarily increase.

Cites

  • No record.

    • References

  • No record.

    • Cite

    APA: Copy

    KHAMOUSHI, AMIR JAMSHID, KASHFI, FAHIMEH, HOSSEINI, SAEID, SAMIEI, NILOUFAR, & HADDADZADEH, MEHDI. (2011). ANTI-COAGULATION DURING PREGNANCY IN WOMEN WITH MECHANICAL HEART VALVES: A PROSPECTIVE STUDY. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 5(1), 47-51. SID. https://sid.ir/paper/304734/en

    Vancouver: Copy

    KHAMOUSHI AMIR JAMSHID, KASHFI FAHIMEH, HOSSEINI SAEID, SAMIEI NILOUFAR, HADDADZADEH MEHDI. ANTI-COAGULATION DURING PREGNANCY IN WOMEN WITH MECHANICAL HEART VALVES: A PROSPECTIVE STUDY. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2011;5(1):47-51. Available from: https://sid.ir/paper/304734/en

    IEEE: Copy

    AMIR JAMSHID KHAMOUSHI, FAHIMEH KASHFI, SAEID HOSSEINI, NILOUFAR SAMIEI, and MEHDI HADDADZADEH, “ANTI-COAGULATION DURING PREGNANCY IN WOMEN WITH MECHANICAL HEART VALVES: A PROSPECTIVE STUDY,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 5, no. 1, pp. 47–51, 2011, [Online]. Available: https://sid.ir/paper/304734/en

    Related Journal Papers

  • No record.

    • Related Seminar Papers

  • No record.

    • Related Plans

  • No record.

    • Recommended Workshops






    Move to top
    telegram sharing button
    whatsapp sharing button
    linkedin sharing button
    twitter sharing button
    email sharing button
    email sharing button
    email sharing button
    sharethis sharing button