COMPARATIVE STUDY OF THE EFFECTS OF DAILY AND TWO TIME PER DAY APPLICATION OF HONEY ON OPEN SKIN WOUND HEALING PROCESS OF RATS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

BAYAT M.; HOSSEINI A.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Daneshvar Medicine: Basic and Clinical Research Journal Year:2001 | Volume:8 | Issue:30 Page(s): 31-36

Download Full-Text

Persian Verion

View:

1,024

Download:

Cites:

Information Journal Paper

Title

COMPARATIVE STUDY OF THE EFFECTS OF DAILY AND TWO TIME PER DAY APPLICATION OF HONEY ON OPEN SKIN WOUND HEALING PROCESS OF RATS

Author(s)

BAYAT M. | HOSSEINI A. | Issue Writer Certificate

Keywords

HONEYQ2

WOUND HEALING. SKINQ4

CELL COUNTQ4

RATQ2

Abstract

In this study the effects of daily and two time per day application of HONEY on open skin wound healing of RAT by CELL COUNT method were compared.Forty eight male adult RATs were randomly divided into control and experimental groups. Each group divided into 3 subgroups based on duration of wound healing (4,7 and 14 days). Under general anesthesia and sterilsconditions, on the skin of dorsum of neck of each RAT, one full thickness circular wound were made.Immediately after wounding, the wounds of RAT number one and two of experimental group were covered with un boiled and unprocessed HONEY daily or 2 time per day. The day of wounding was assumed as day zero. At the end, RATs were killed by ether, sample were obtained from wound bed and normal adjacent skin. Samples were prepared for routine histological study and sections were stained by hematoxyline and eosine method. Fibroblasts, macrophages, neutrophils and endothelium of vessels of wound bed were counted by special eyepiece. Depth of wound bed and depth of new epidermis were calculated by special eyepiece. Data of groups were analysed by analysis of varience method.Result showed a significant differences amoung fibroblast, macrophages, neutrophils and depth of wound. Secondary analyis of data, by least significant difference method revealed that following groups had significant differences with each other. At fourth day: 1) Between fibroblasts and macrophages of control and experimental groups 2) Between neutrophils and depth of wound of experimental groups with each other and also number 2 of experimental group with control group. At seventh day:1) Between fibrobsts of experimental groups with each other and also with control group. 2) Between macrophages of number 2 of experimental group with other groups. At fourteenth day; between fibrobalst of experimental groups with each other.Two time per day application of HONEY on open skin wound of RATs accelerated wound healing process more significantly in comparison with daily application of HONEY.

Cites

EVALUATION OF EFFECT OF COMPUND OF OLEA EUROPEA L. AND MYRTUS COMMUNIS L. ON BURN WOUND HEALING

References

Cite

APA: Copy

BAYAT, M., & HOSSEINI, A.. (2001). COMPARATIVE STUDY OF THE EFFECTS OF DAILY AND TWO TIME PER DAY APPLICATION OF HONEY ON OPEN SKIN WOUND HEALING PROCESS OF RATS. DANESHVAR MEDICINE, 8(30), 31-36. SID. https://sid.ir/paper/30483/en

Vancouver: Copy

BAYAT M., HOSSEINI A.. COMPARATIVE STUDY OF THE EFFECTS OF DAILY AND TWO TIME PER DAY APPLICATION OF HONEY ON OPEN SKIN WOUND HEALING PROCESS OF RATS. DANESHVAR MEDICINE[Internet]. 2001;8(30):31-36. Available from: https://sid.ir/paper/30483/en

IEEE: Copy

M. BAYAT, and A. HOSSEINI, “COMPARATIVE STUDY OF THE EFFECTS OF DAILY AND TWO TIME PER DAY APPLICATION OF HONEY ON OPEN SKIN WOUND HEALING PROCESS OF RATS,” DANESHVAR MEDICINE, vol. 8, no. 30, pp. 31–36, 2001, [Online]. Available: https://sid.ir/paper/30483/en

Related Journal Papers