A SURVEY ON ALPHA1 ANTITRYPSIN IN, PATIENTS WITH UVEITIS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

GHAVAMI S.; HASHEMI M.; TAHERI MOHSEN; SHAHRYARI H.A.; KAZEMNEJAD ANOUSHIRAVAN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: DANESHVAR MEDICINE Year:2002 | Volume:10 | Issue:41 (Special Edition on Medical Sciences Articles) Page(s): 37-46

Download Full-Text

Persian Verion

View:

1,196

Download:

Cites:

Information Journal Paper

Title

A SURVEY ON ALPHA1 ANTITRYPSIN IN, PATIENTS WITH UVEITIS

Author(s)

Keywords

ALPHA1 ANTITRYPSINQ3

UVEITISQ3

INFLAMMATORY EYE DISEASEQ2

ISOELECTRIC FOCUSINGQ3

Abstract

ALPHA1 ANTITRYPSIN (α1AT) is a glycoprotein which is synthesized in liver hepatocytes. It is an acute phase protein and its molecular weight is about 52 KD. This protein is expressed by two alleles on chromosome 14, codominantly. The most important function of this protein is the inhibition of serine proteases, therefore it is, classified in SERPIN (serine protease inhibitor) family. AAT has several alleles. These alleles are classified in normal (M1, M2, M3, M4, M5, ...), severe deficient (Z), moderate deficient (S), and null forms. ALPHA1 ANTITRYPSIN deficiency might be a risk factor for several diseases like neonatal and infantile liver disease, emphysema, asthma, arthristis rheumatic disease, glumeronephritis, and INFLAMMATORY EYE DISEASE.on the other hand, UVEITIS is an INFLAMMATORY EYE DISEASE. Immune system disorder, infectious disease, genetic and environmental factor might have important role in the etiology of this disease. UVEITIS is divided in to anterior, posterior, panuveitis, and pars planitis forms. According to the role of immune system in UVEITIS and the regulation of this system by AAT, this research was designed. In this research 103 UVEITIS patients who referred to Zahedan Al-Zahra Ophthalmology center were investigated (from 1996 through 1998) and compared with 167 individuals without any eye or systemic disease. According to our result, in UVEITIS group 63 individuals had normal phenotypes (M1M2, M1M1 and M2M2), 14 M1S, 9 M2S, 10 M1Z, 3 MZ, and 4 MV phenotype. But in normal group, 160 individuals had normal phenotypes (M1M2, M1M1, and M2M2), 3 M1S, 1 M2S, and 3 M1Z phenotype. Therefore, there is a significant difference between abnormal phenotypes in patients and UVEITIS group (P<0.0001).

Cites

References

No record.

Cite

APA: Copy

GHAVAMI, S., HASHEMI, M., TAHERI, MOHSEN, SHAHRYARI, H.A., & KAZEMNEJAD, ANOUSHIRAVAN. (2002). A SURVEY ON ALPHA1 ANTITRYPSIN IN, PATIENTS WITH UVEITIS. DANESHVAR MEDICINE, 10(41 (Special Edition on Medical Sciences Articles)), 37-46. SID. https://sid.ir/paper/30493/en

Vancouver: Copy

GHAVAMI S., HASHEMI M., TAHERI MOHSEN, SHAHRYARI H.A., KAZEMNEJAD ANOUSHIRAVAN. A SURVEY ON ALPHA1 ANTITRYPSIN IN, PATIENTS WITH UVEITIS. DANESHVAR MEDICINE[Internet]. 2002;10(41 (Special Edition on Medical Sciences Articles)):37-46. Available from: https://sid.ir/paper/30493/en

IEEE: Copy

S. GHAVAMI, M. HASHEMI, MOHSEN TAHERI, H.A. SHAHRYARI, and ANOUSHIRAVAN KAZEMNEJAD, “A SURVEY ON ALPHA1 ANTITRYPSIN IN, PATIENTS WITH UVEITIS,” DANESHVAR MEDICINE, vol. 10, no. 41 (Special Edition on Medical Sciences Articles), pp. 37–46, 2002, [Online]. Available: https://sid.ir/paper/30493/en

Related Journal Papers