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Information Journal Paper

Title

INCREASED ACTIVITY IN THE FORM OF ENDURANCE TRAINIG INCREASES CALCITONIN GENE-RELATED PEPTIDE CONTENT IN LUMBAR MOTONEURON CELL BODIES IN THE RAT

Pages

  19-32

Abstract

 The relative content of calcitonin gene-related peptide in lumb or MOTONEURON cell bodies (semi-quantitative immunohistochemistry) was examined in RATs who had previously undergone for 16-weeks period of endurance training on a motor-driven treadmill. Soleus MOTONEURONs were identified in the spinal cord by their fluorescence following injection of Fluorogold into the muscle one week before killing. In Sedentary RATs, calcitonin gene-related peptide was detectable in 76-90% of MOTONEURONs, with no difference in the proportions of negative cells, or in the mean staining intensity of positive cells, between soleus and neighboring (presumptive fast hindlimb muscle) unlabelled MOTONEURONs. In endurance - trained RATs, the estimated content of calcitonin gene-related peptide was significantly increased (90%) in cell bodies of soleus and neighboring MOTONEURONs, with no training-induced alterations  in the proportions of calcitonin gene-related peptide positive cells in either sample. The increases in calcitonin gene-related peptide in MOTONEURON cell bodies following endurance training may indicate an up-regulation of the synthesis, transport and terminal release of this neuropeptide, which could play a significant role in other morphological and functional adaptations which are known to occur at the NEUROMUSCULAR JUNCTION following the chronic change in ACTIVITY level.

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    APA: Copy

    GHARAKHANLOU, R.. (2002). INCREASED ACTIVITY IN THE FORM OF ENDURANCE TRAINIG INCREASES CALCITONIN GENE-RELATED PEPTIDE CONTENT IN LUMBAR MOTONEURON CELL BODIES IN THE RAT. DANESHVAR MEDICINE, 10(41 (Special Edition on Medical Sciences Articles)), 19-32. SID. https://sid.ir/paper/30496/en

    Vancouver: Copy

    GHARAKHANLOU R.. INCREASED ACTIVITY IN THE FORM OF ENDURANCE TRAINIG INCREASES CALCITONIN GENE-RELATED PEPTIDE CONTENT IN LUMBAR MOTONEURON CELL BODIES IN THE RAT. DANESHVAR MEDICINE[Internet]. 2002;10(41 (Special Edition on Medical Sciences Articles)):19-32. Available from: https://sid.ir/paper/30496/en

    IEEE: Copy

    R. GHARAKHANLOU, “INCREASED ACTIVITY IN THE FORM OF ENDURANCE TRAINIG INCREASES CALCITONIN GENE-RELATED PEPTIDE CONTENT IN LUMBAR MOTONEURON CELL BODIES IN THE RAT,” DANESHVAR MEDICINE, vol. 10, no. 41 (Special Edition on Medical Sciences Articles), pp. 19–32, 2002, [Online]. Available: https://sid.ir/paper/30496/en

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    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
    مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources
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