THE EFFECT OF FLUTAMIDE ON OVULATION INDUCTION IN PCOS PATIENTS

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MADANI TAHEREH; IRANI SHOHREH; ASHRAFI MAHNAZ; NABAVI MARYAM ALSADAT

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Journal Paper

Paper Information

Journal: International Journal of Fertility & Sterility Year:2012 | Volume:6 | Issue:1 Page(s): 65-70

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Title

THE EFFECT OF FLUTAMIDE ON OVULATION INDUCTION IN PCOS PATIENTS

Author(s)

MADANI TAHEREH | IRANI SHOHREH | ASHRAFI MAHNAZ | NABAVI MARYAM ALSADAT | Issue Writer Certificate

Keywords

POLYCYSTIC OVARY SYNDROME

FLUTAMIDE

OVULATION INDUCTION

Abstract

Background: POLYCYSTIC OVARY SYNDROME (PCOS) is a disorder that affects various body organs and requires comprehensive long term evaluation and management. The aim of this study was to evaluate effect of FLUTAMIDE on OVULATION INDUCTION in PCOS patients. Materials and Methods: This prospective study applied triple blind method, a simple convenience sampling method, to induce ovulations of the ninety six PCOS patients. Patients were divided into two groups; group A included 53 subjects (received FLUTAMIDE+Clomiphene Citrate) and group B included 43 subjects (received placebo+Clomiphene Citrate). Ultrasound was carried to determine the size of follicles and growth rate of them during follicular phase of the menstrual cycle. Also, progesterone levels were measured on days 19 and 21 of the menstrual cycle.Results: In this study, ninety six PCOS patients, in two treatment and control groups, were evaluated regarding to body mass index (BMI), cycle irregularity, age and number of dominant follicles, duration of stimulation, endocrine profile and score of hirsutism. The obtained results revealed no significant differences between two groups.Conclusion: FLUTAMIDE does not affect ovulation improvement in PCOS patients undergoing induction.

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APA: Copy

MADANI, TAHEREH, IRANI, SHOHREH, ASHRAFI, MAHNAZ, & NABAVI, MARYAM ALSADAT. (2012). THE EFFECT OF FLUTAMIDE ON OVULATION INDUCTION IN PCOS PATIENTS. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 6(1), 65-70. SID. https://sid.ir/paper/304998/en

Vancouver: Copy

MADANI TAHEREH, IRANI SHOHREH, ASHRAFI MAHNAZ, NABAVI MARYAM ALSADAT. THE EFFECT OF FLUTAMIDE ON OVULATION INDUCTION IN PCOS PATIENTS. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2012;6(1):65-70. Available from: https://sid.ir/paper/304998/en

IEEE: Copy

TAHEREH MADANI, SHOHREH IRANI, MAHNAZ ASHRAFI, and MARYAM ALSADAT NABAVI, “THE EFFECT OF FLUTAMIDE ON OVULATION INDUCTION IN PCOS PATIENTS,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 6, no. 1, pp. 65–70, 2012, [Online]. Available: https://sid.ir/paper/304998/en

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