EFFECT OF PROGESTERONE SUPPLEMENTATION ON NATURAL FROZEN-THAWED EMBRYO TRANSFER CYCLES: A RANDOMIZED CONTROLLED TRIAL

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EFTEKHAR MARYAM; RAHSEPAR MOZHGAN; RAHMANI ELHAM

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Journal Paper

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Journal: International Journal of Fertility & Sterility Year:2013 | Volume:7 | Issue:1 Page(s): 13-20

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Title

EFFECT OF PROGESTERONE SUPPLEMENTATION ON NATURAL FROZEN-THAWED EMBRYO TRANSFER CYCLES: A RANDOMIZED CONTROLLED TRIAL

Author(s)

EFTEKHAR MARYAM | RAHSEPAR MOZHGAN | RAHMANI ELHAM | Issue Writer Certificate

Keywords

PROGESTERONE

PREGNANCY RATE

EMBRYO TRANSFER

NATURAL CYCLE

Abstract

Background: The transfer of cryopreserved embryos can be timed with ovulation in a NATURAL CYCLE or after artificially preparing the endometrium with exogenous hormones. PROGESTERONE is essential for the secretory transformation of the endometrium that permits implantation as well as maintenance of early pregnancy. The purpose of this study is to assess the effect of luteal phase supplementation on PREGNANCY RATEs in natural frozen-thawed cycles.Materials and Methods: The study was designed as a prospective randomized clinical trial of 102 women who underwent EMBRYO TRANSFERs in NATURAL CYCLEs. The women in the interventional group (n=51) received intra muscular (IM) PROGESTERONE 50 mg twice a day starting from 36 hours after hCG administration. The control group (n=51) did not receive any PROGESTERONE support.Results: There were no significant differences in demographic characteristics between the groups and no statistically significant differences were observed between study and control groups in clinical PREGNANCY RATE (33.3% vs.27.5%, p=0.66). There were no differences in implantation rate or spontaneous abortion rate.Conclusion: Our results suggest that luteal phase support does not affect clinical PREGNANCY RATEs in natural frozen-thawed EMBRYO TRANSFER cycles (Registration Number: IRCT201108044339N6).

Cites

BISHOP SCORE PREDICTIVE VALUE IN SUCCESS OF INDUCED LABOR PROCESS AMONG FULL TERM PREGNANT WOMEN REFERRED TO PERSIAN GULF MARTYRS’ HOSPITAL IN BUSHEHR IN 2013

References

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APA: Copy

EFTEKHAR, MARYAM, RAHSEPAR, MOZHGAN, & RAHMANI, ELHAM. (2013). EFFECT OF PROGESTERONE SUPPLEMENTATION ON NATURAL FROZEN-THAWED EMBRYO TRANSFER CYCLES: A RANDOMIZED CONTROLLED TRIAL. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 7(1), 13-20. SID. https://sid.ir/paper/305397/en

Vancouver: Copy

EFTEKHAR MARYAM, RAHSEPAR MOZHGAN, RAHMANI ELHAM. EFFECT OF PROGESTERONE SUPPLEMENTATION ON NATURAL FROZEN-THAWED EMBRYO TRANSFER CYCLES: A RANDOMIZED CONTROLLED TRIAL. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2013;7(1):13-20. Available from: https://sid.ir/paper/305397/en

IEEE: Copy

MARYAM EFTEKHAR, MOZHGAN RAHSEPAR, and ELHAM RAHMANI, “EFFECT OF PROGESTERONE SUPPLEMENTATION ON NATURAL FROZEN-THAWED EMBRYO TRANSFER CYCLES: A RANDOMIZED CONTROLLED TRIAL,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 7, no. 1, pp. 13–20, 2013, [Online]. Available: https://sid.ir/paper/305397/en

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