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Information Journal Paper

Title

THE EFFECTS OF ISM1 MEDIUM ON EMBRYO QUALITY AND OUTCOMES OF IVF/ICSI CYCLES

Pages

  108-115

Abstract

 Background: The aim of this study is to investigate the effect of ISM1 culture medium on EMBRYO development, QUALITY and outcomes of in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles. This study compares culture medium commonly used in the laboratory setting for oocyte recovery and EMBRYO development with a medium from MediCult. We have assessed the effects of these media on EMBRYO development and newborn characteristics.Materials and Methods: In this prospective randomized study, fertilized oocytes from patients were randomly assigned to culture in ISM1 (MediCult, cycles: n=293) or routine lab culture medium (G-1TM v5; Vitrolife, cycles: n=290) according to the daily media schedule for oocyte retrieval. IVF or ICSI and EMBRYO transfer were performed with either MediCult media or routine lab media. EMBRYO QUALITY on days 2/3, cleavage, pregnancy and implantation rates, baby take home rate (BTHR), in addition to the weight and length of newborns were compared between groups. Results: There were similar cleavage rates for ISM1 (86%) vs. G-1TM v5 (88%). We observed a significantly higher percentage of excellent EMBRYOs in ISM1 (42.7%) compared to G-1TM v5 (39%, p<0.05). Babies born after culture in ISM1 had both higher BIRTH WEIGHT (3.03 kg) and length (48.8 cm) compared to G-1TM v5 babies that had a BIRTH WEIGHT of 2.66 kg and a length of 46.0 cm (p<0.001 for both).Conclusion: This study suggests that ISM1 is a more effective culture medium in generating higher QUALITY EMBRYOs, which may be reflected in the characteristics of babies at birth.

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    APA: Copy

    HASANI, FATEMEH, EFTEKHARI YAZDI, POOPAK, KARIMIAN, LEILA, REZAZADEH VALOJERDI, MOJTABA, MOVAGHAR, BAHAR, FAZEL, MOHAMMAD, FOULADI, HAMID REZA, SHABANI, FATEMEH, & JOHANSSON, LARS. (2013). THE EFFECTS OF ISM1 MEDIUM ON EMBRYO QUALITY AND OUTCOMES OF IVF/ICSI CYCLES. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 7(2), 108-115. SID. https://sid.ir/paper/305405/en

    Vancouver: Copy

    HASANI FATEMEH, EFTEKHARI YAZDI POOPAK, KARIMIAN LEILA, REZAZADEH VALOJERDI MOJTABA, MOVAGHAR BAHAR, FAZEL MOHAMMAD, FOULADI HAMID REZA, SHABANI FATEMEH, JOHANSSON LARS. THE EFFECTS OF ISM1 MEDIUM ON EMBRYO QUALITY AND OUTCOMES OF IVF/ICSI CYCLES. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2013;7(2):108-115. Available from: https://sid.ir/paper/305405/en

    IEEE: Copy

    FATEMEH HASANI, POOPAK EFTEKHARI YAZDI, LEILA KARIMIAN, MOJTABA REZAZADEH VALOJERDI, BAHAR MOVAGHAR, MOHAMMAD FAZEL, HAMID REZA FOULADI, FATEMEH SHABANI, and LARS JOHANSSON, “THE EFFECTS OF ISM1 MEDIUM ON EMBRYO QUALITY AND OUTCOMES OF IVF/ICSI CYCLES,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 7, no. 2, pp. 108–115, 2013, [Online]. Available: https://sid.ir/paper/305405/en

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