COMPARISON OF CONGENITAL ABNORMALITIES OF INFANTS CONCEIVED BY ASSISTED REPRODUCTIVE TECHNIQUES VERSUS INFANTS WITH NATURAL CONCEPTION IN TEHRAN

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

FARHANGNIYA MANSOUREH; DORTAJ RABORI ESHAGH; MOZAFARI KERMANI RAMIN; HAGHDOOST ALI AKBAR; BAHRAMPOUR ABBAS; BAGHERI PEZHMAN; L. LANCASTER PAUL A.; ASHRAFI MAHNAZ; TAQI DIZAJ AHMAD VOSOUGH; GOURABI HAMID; SHAHZADEH FAZELI ABOLHASSAN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: International Journal of Fertility & Sterility Year:2013 | Volume:7 | Issue:3 Page(s): 217-224

Download Full-Text

View:

421

Download:

190

Cites:

Information Journal Paper

Title

COMPARISON OF CONGENITAL ABNORMALITIES OF INFANTS CONCEIVED BY ASSISTED REPRODUCTIVE TECHNIQUES VERSUS INFANTS WITH NATURAL CONCEPTION IN TEHRAN

Author(s)

Keywords

INFANTS

ASSISTED REPRODUCTIVE TECHNIQUE

CONGENITAL MALFORMATIONS

ANOMALY

CONCEPTION

FERTILIZATION

Abstract

Background: In many countries, 1 to 3% of newborn INFANTS are conceived by ASSISTED REPRODUCTIVE TECHNIQUEs (ART). Despite the success of ART, there is concern about the risk of CONGENITAL MALFORMATIONS among these INFANTS. We report our experience to determine whether use of ART is associated with an increase in major CONGENITAL MALFORMATIONS or adverse pregnancy outcomes.Materials and Methods: Historical cohort study of major CONGENITAL MALFORMATIONS (MCM) was performed in 978 births from January 2008 to December 2010. The data for this analysis were derived from a Tehran’s ART linked data file by simple sampling method. In our study, the risk of CONGENITAL MALFORMATIONS was compared in 326 ART INFANTS and 652 naturally conceived (NC) INFANTS. We also performed multiple logistic regression analyses to calculate the odds ratio (OR) and 95% confidence intervals (CI) for the independent association of ART on each outcome.Results: We found 56 INFANTS with major CONGENITAL MALFORMATIONS, these included 29 NC INFANTS (4.4%) and 27 ART INFANTS (8.3%). In comparison with NC INFANTS, ART INFANTS had a significant 1.94-fold increased risk of MCM. After adjustment for maternal age, infant's sex stillbirth, abortion and type of delivery, we found a relatively small difference in risk (OR=2.04). In this study the majority (94.3%) of all INFANTS were normal but 5.7% of INFANTS had at least one MCM. The prevalence rate for the intracytoplasmic sperm injection (ICSI) was 6.5% for the In vitro fertilisation (IVF) group was 15.9% or 2.73-fold higher than ICSI group (P=0.018). Also we ignore the possible role of genotype and other unknown factors in causing more malformations in ART INFANTS.Conclusion: Other studies have shown a slightly increased risk of major CONGENITAL MALFORMATIONS in pregnancies resulting from ART. Likewise, this study reports a greater risk of MCMs in ART INFANTS than in naturally conceived INFANTS. We also found evidence of a difference in risk of MCMs between IVF and ICSI. Musculoskeletal and urogenital malformations were the most reported MCMs in ART INFANTS according to organs and systems classification.

Cites

No record.

References

Cite

APA: Copy

FARHANGNIYA, MANSOUREH, DORTAJ RABORI, ESHAGH, MOZAFARI KERMANI, RAMIN, HAGHDOOST, ALI AKBAR, BAHRAMPOUR, ABBAS, BAGHERI, PEZHMAN, L. LANCASTER, PAUL A., ASHRAFI, MAHNAZ, TAQI DIZAJ, AHMAD VOSOUGH, GOURABI, HAMID, & SHAHZADEH FAZELI, ABOLHASSAN. (2013). COMPARISON OF CONGENITAL ABNORMALITIES OF INFANTS CONCEIVED BY ASSISTED REPRODUCTIVE TECHNIQUES VERSUS INFANTS WITH NATURAL CONCEPTION IN TEHRAN. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 7(3), 217-224. SID. https://sid.ir/paper/305419/en

Vancouver: Copy

FARHANGNIYA MANSOUREH, DORTAJ RABORI ESHAGH, MOZAFARI KERMANI RAMIN, HAGHDOOST ALI AKBAR, BAHRAMPOUR ABBAS, BAGHERI PEZHMAN, L. LANCASTER PAUL A., ASHRAFI MAHNAZ, TAQI DIZAJ AHMAD VOSOUGH, GOURABI HAMID, SHAHZADEH FAZELI ABOLHASSAN. COMPARISON OF CONGENITAL ABNORMALITIES OF INFANTS CONCEIVED BY ASSISTED REPRODUCTIVE TECHNIQUES VERSUS INFANTS WITH NATURAL CONCEPTION IN TEHRAN. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2013;7(3):217-224. Available from: https://sid.ir/paper/305419/en

IEEE: Copy

MANSOUREH FARHANGNIYA, ESHAGH DORTAJ RABORI, RAMIN MOZAFARI KERMANI, ALI AKBAR HAGHDOOST, ABBAS BAHRAMPOUR, PEZHMAN BAGHERI, PAUL A. L. LANCASTER, MAHNAZ ASHRAFI, AHMAD VOSOUGH TAQI DIZAJ, HAMID GOURABI, and ABOLHASSAN SHAHZADEH FAZELI, “COMPARISON OF CONGENITAL ABNORMALITIES OF INFANTS CONCEIVED BY ASSISTED REPRODUCTIVE TECHNIQUES VERSUS INFANTS WITH NATURAL CONCEPTION IN TEHRAN,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 7, no. 3, pp. 217–224, 2013, [Online]. Available: https://sid.ir/paper/305419/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops