COMPARISON OF 25-HYDROXYVITAMIN D AND CALCIUM LEVELS BETWEEN POLYCYSTIC OVARIAN SYNDROME AND NORMAL WOMEN

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MOINI ASHRAF; SHIRZAD NOOSHIN; AHMADZADEH MARZIEH; HOSSEINI REIHANEH; HOSSEINI LADAN; JAHANIAN SADATMAHALLEH SHAHIDEH

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Journal: International Journal of Fertility & Sterility Year:2015 | Volume:9 | Issue:1 Page(s): 1-8

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Title

COMPARISON OF 25-HYDROXYVITAMIN D AND CALCIUM LEVELS BETWEEN POLYCYSTIC OVARIAN SYNDROME AND NORMAL WOMEN

Author(s)

Keywords

POLYCYSTIC OVARY SYNDROME

25-HYDROXYVITAMIN D

CALCIUM

Abstract

Background: Given the relationship of vitamin D deficiency with insulin resistance syndrome as the component of POLYCYSTIC OVARY SYNDROME (PCOS), the main aim of this study was to compare serum level of 25- hydroxyvitamin D [25 (OH) D] between PCOS patients and normal individuals.Materials and Methods: A cross sectional study was conducted to compare 25 (OH) D level between117 normal and 125 untreated PCOS cases at our clinic in Arash Hospital, Tehran, Iran, during 2011-2012. The obtained levels of 25 (OH) D were classified as follows: lower than 25 nmol/ml as severe deficiency, between 25-49.9 nmol/ml as deficiency, 50-74.9 nmol/ml as insufficiency, and above 75 nmol/ml asnormal. In addition, endocrine and metabolic variables were evaluated.Results: Among PCOS patients, our findings shows 3 (2.4%) normal, 7 (5.6%) with insufficiency, 33 (26.4%) with deficiency and 82 (65.6%) with severe deficiency, whereas in normal participants, 5 (4.3%) normal, 4 (3.4%) with insufficiency, 28 (23.9%) with deficiency and 80 (68.4%) with severe deficiency. Comparison of 25 (OH) D level between two main groups showed no significant differences (p=0.65). Also, the CALCIUM and 25 (OH) D levels had no significant differences in patients with overweight (p=0.22) and insulin resistance (p=0.64). But we also found a relationship between 25 (OH) D level and metabolic syndrome (p=0.01). Furthermore, there was a correlation between 25 (OH) D and body mass index (BMI) in control group (p=0.01), while the C-reactive protein (CRP) level was predominantly higher in PCOS group (p<0.001).Conclusion: Although the difference of 25 (OH) D level between PCOS and healthy women is not significant, the high prevalence of 25 (OH) D deficiency is a real alarm for public health care system and may influence our results.

Cites

COMPARISON OF VITAMIN D DEFICIENCY IN WOMEN WITH POLYCYSTIC OVARY SYNDROME WHO REFERRED TO INFERTILITY CLINIC WITH CONTROL GROUP

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APA: Copy

MOINI, ASHRAF, SHIRZAD, NOOSHIN, AHMADZADEH, MARZIEH, HOSSEINI, REIHANEH, HOSSEINI, LADAN, & JAHANIAN SADATMAHALLEH, SHAHIDEH. (2015). COMPARISON OF 25-HYDROXYVITAMIN D AND CALCIUM LEVELS BETWEEN POLYCYSTIC OVARIAN SYNDROME AND NORMAL WOMEN. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 9(1), 1-8. SID. https://sid.ir/paper/305797/en

Vancouver: Copy

MOINI ASHRAF, SHIRZAD NOOSHIN, AHMADZADEH MARZIEH, HOSSEINI REIHANEH, HOSSEINI LADAN, JAHANIAN SADATMAHALLEH SHAHIDEH. COMPARISON OF 25-HYDROXYVITAMIN D AND CALCIUM LEVELS BETWEEN POLYCYSTIC OVARIAN SYNDROME AND NORMAL WOMEN. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2015;9(1):1-8. Available from: https://sid.ir/paper/305797/en

IEEE: Copy

ASHRAF MOINI, NOOSHIN SHIRZAD, MARZIEH AHMADZADEH, REIHANEH HOSSEINI, LADAN HOSSEINI, and SHAHIDEH JAHANIAN SADATMAHALLEH, “COMPARISON OF 25-HYDROXYVITAMIN D AND CALCIUM LEVELS BETWEEN POLYCYSTIC OVARIAN SYNDROME AND NORMAL WOMEN,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 9, no. 1, pp. 1–8, 2015, [Online]. Available: https://sid.ir/paper/305797/en

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