ASSOCIATION OF GLOMERULAR FILTRATION RATE WITH INFLAMMATION IN POLYCYSTIC OVARY SYNDROME

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GOZUKARA ILAY OZTURK; GOZUKARA KEREM HAN; KABIL KUCUR SUNA; ULKU KARAKILIC EDA; KESKIN HAVVA; AKDENIZ DERYA; AKSOY AYSE NUR; CARLIOGLU AYSE

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Journal: International Journal of Fertility & Sterility Year:2015 | Volume:9 | Issue:2 Page(s): 176-182

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Title

ASSOCIATION OF GLOMERULAR FILTRATION RATE WITH INFLAMMATION IN POLYCYSTIC OVARY SYNDROME

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Keywords

CRP

GLOMERULAR FILTRATION RATE

POLYCYSTIC OVARY SYNDROME

URIC ACID

Abstract

Background: We aimed to estimate the GLOMERULAR FILTRATION RATE (GFR) in women with POLYCYSTIC OVARY SYNDROME (PCOS) and to determine the relationship between GFR with C-reactive protein (CRP) and URIC ACID.Materials and Methods: In this cross-sectional study, one-hundred and forty PCOS women and 60 healthy subjects were evaluated. The study was carried out at Endocrinology Outpatient Clinic, Erzurum Training and Research Hospital, Erzurum, Turkey, from December 2010 to January 2011. GFRs were estimated by Modification of Diet in Renal Disease (MDRD) formula. CRP, urinary albumin excretion (UAE) and URIC ACID levels were also measured.Results: GFRs were significantly higher in PCOS group than control (135.24±25.62 vs. 114.92±24.07 ml/min per 1.73 m2). CRP levels were significantly higher in PCOS patients (4.4±3.4 vs. 2.12±1.5 mg/l). The PCOS group had significantly higher serum URIC ACID levels (4.36±1.3 mg/dl vs. 3.2±0.73 mg/dl). There was also significantly higher proteinuria level in PCOS patients.Conclusion: Even though PCOS patients had higher GFR, serum URIC ACID and UAE values than control patients, the renal function was within normal limits. Increased GFR in PCOS women positively correlates with elevated serum CRP and URIC ACID.

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APA: Copy

GOZUKARA, ILAY OZTURK, GOZUKARA, KEREM HAN, KABIL KUCUR, SUNA, ULKU KARAKILIC, EDA, KESKIN, HAVVA, AKDENIZ, DERYA, AKSOY, AYSE NUR, & CARLIOGLU, AYSE. (2015). ASSOCIATION OF GLOMERULAR FILTRATION RATE WITH INFLAMMATION IN POLYCYSTIC OVARY SYNDROME. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 9(2), 176-182. SID. https://sid.ir/paper/305800/en

Vancouver: Copy

GOZUKARA ILAY OZTURK, GOZUKARA KEREM HAN, KABIL KUCUR SUNA, ULKU KARAKILIC EDA, KESKIN HAVVA, AKDENIZ DERYA, AKSOY AYSE NUR, CARLIOGLU AYSE. ASSOCIATION OF GLOMERULAR FILTRATION RATE WITH INFLAMMATION IN POLYCYSTIC OVARY SYNDROME. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2015;9(2):176-182. Available from: https://sid.ir/paper/305800/en

IEEE: Copy

ILAY OZTURK GOZUKARA, KEREM HAN GOZUKARA, SUNA KABIL KUCUR, EDA ULKU KARAKILIC, HAVVA KESKIN, DERYA AKDENIZ, AYSE NUR AKSOY, and AYSE CARLIOGLU, “ASSOCIATION OF GLOMERULAR FILTRATION RATE WITH INFLAMMATION IN POLYCYSTIC OVARY SYNDROME,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 9, no. 2, pp. 176–182, 2015, [Online]. Available: https://sid.ir/paper/305800/en

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