MOLECULAR EVIDENCE OF CHLAMYDIA TRACHOMATIS INFECTION AND ITS RELATION TO MISCARRIAGE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

BAGHERI SAHAR; ROGHANIAN RASOUL; GOLBANG NASER; GOLBANG POURAN; NASR ESFAHANI MOHAMMAD HOSSEIN

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: International Journal of Fertility & Sterility Year:2018 | Volume:12 | Issue:2 Page(s): 152-156

Download Full-Text

View:

235

Download:

292

Cites:

Information Journal Paper

Title

MOLECULAR EVIDENCE OF CHLAMYDIA TRACHOMATIS INFECTION AND ITS RELATION TO MISCARRIAGE

Author(s)

Keywords

CHLAMYDIA TRACHOMATIS

ENZYME-LINKED IMMUNOSORBENT ASSAY

MISCARRIAGE

POLYMERASE CHAIN REACTION

Abstract

Background: CHLAMYDIA TRACHOMATIS (CT) infection is the most common sexually transmitted disease in the world that can persist and also ascend in the genital tract. This intracellular and silent infection is related to some adverse pregnancy outcomes, such as MISCARRIAGE. The aims of this study were to explore the best CT screening tests using blood and vaginal samples and to investigate the correlation between CT infection and the incidence of MISCARRIAGE.Materials and Methods: This case-control study was done in October 2013 through June 2014, using purposive sampling from 157 female participants with or without a history of MISCARRIAGE. The samples were taken after each participant had signed a letter of consent and had completed a questionnaire. To achieve the objectives of this study, POLYMERASE CHAIN REACTION (PCR) and ENZYME-LINKED IMMUNOSORBENT ASSAY (ELISA) tests were performed on vaginal swabs and blood samples, respectively.Results: PCR results showed a significantly higher CT infection rate in the MISCARRIAGE group compared to the control group (11.3 vs.0%, P=0.007). Anti-CT IgG and IgA antibodies were found in 4.2 and 2.1% of cases in the MISCARRIAGE group, and in 1.7 and 6.7% of cases in the control group, respectively (P>0.05). Despite lower humoral responses in this study, positive samples were detected only by one of the following techniques; PCR, ELISA IgA and ELISA IgG. It also should be noted that PCR worked best in terms of detection.Conclusion: Based on the obtained data, there is a strong association between molecular evidence of CT infection and MISCARRIAGE. A higher rate of CT detection in molecular tests compared to serological assays suggests that PCR could be used as the first-choice assay for detection of C. trachomatis. However, the importance of serological tests in detecting potential past CT infection or upper genital infection not amenable to sampling is undeniable.

Cites

No record.

References

No record.

Cite

APA: Copy

BAGHERI, SAHAR, ROGHANIAN, RASOUL, GOLBANG, NASER, GOLBANG, POURAN, & NASR ESFAHANI, MOHAMMAD HOSSEIN. (2018). MOLECULAR EVIDENCE OF CHLAMYDIA TRACHOMATIS INFECTION AND ITS RELATION TO MISCARRIAGE. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 12(2), 152-156. SID. https://sid.ir/paper/305981/en

Vancouver: Copy

BAGHERI SAHAR, ROGHANIAN RASOUL, GOLBANG NASER, GOLBANG POURAN, NASR ESFAHANI MOHAMMAD HOSSEIN. MOLECULAR EVIDENCE OF CHLAMYDIA TRACHOMATIS INFECTION AND ITS RELATION TO MISCARRIAGE. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2018;12(2):152-156. Available from: https://sid.ir/paper/305981/en

IEEE: Copy

SAHAR BAGHERI, RASOUL ROGHANIAN, NASER GOLBANG, POURAN GOLBANG, and MOHAMMAD HOSSEIN NASR ESFAHANI, “MOLECULAR EVIDENCE OF CHLAMYDIA TRACHOMATIS INFECTION AND ITS RELATION TO MISCARRIAGE,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 12, no. 2, pp. 152–156, 2018, [Online]. Available: https://sid.ir/paper/305981/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops