مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

EFFECT OF VITAMIN D SUPPLEMENTATION ON INTRACYTOPLASMICSPERM INJECTION OUTCOMES: A RANDOMIZED DOUBLE-BLINDPLACEBO-CONTROLLED TRIAL

Pages

  18-23

Abstract

 Background: Despite numerous studies indicating an imperative role for reproduction, however, the role of VitaminD supplementation on outcomes of ASSISTED REPRODUCTIVE TECHNIQUES remains controversial. This clinical trial was performedto evaluate the effect of VITAMIN D supplementation 6 weeks prior to intracytoplasmic sperm injection (ICSI)on fertility indices. Materials and Methods: The present study was a double-blind clinical trial conducted on infertile women was randomlyallocated into two groups: VITAMIN D supplementation (42 participants) and placebo (43 participants). SerumVitamin D was measured before and six to eight weeks after treatment, on the day of ovum pick up. Results wereanalyzed using SPSS16 and fertility indices were compared between the two groups. Results: No significant difference was observed between the intervention and control groups regarding the meannumber of oocytes retrieved, percentage mature oocyte, fertilization rate and the rate of good quality embryos (allP>0. 05). But, percentages of the individual with suitable endometrium (7-14 mm thickness) were significantly higherin the VITAMIN D compared to control group (P=0. 011). The rate of chemical (47. 6 vs. 25. 5%, P=0. 013) and clinicalpregnancy rate (38. 1 vs. 20. 9%, P=0. 019) were also significantly higher in the VITAMIN D compared to control group. Conclusion: The present study reveals that consuming VITAMIN D for 6 weeks prior to ICSI improves quality of endometrium, rate of chemical and clinical PREGNANCY (Registration Number: IRCT2015111124999N1).

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    APA: Copy

    ABEDI, SARA, TAEBI, MAHBOUBEH, & NASRE ESFAHANI, MOHAMMADHOSEIN. (2019). EFFECT OF VITAMIN D SUPPLEMENTATION ON INTRACYTOPLASMICSPERM INJECTION OUTCOMES: A RANDOMIZED DOUBLE-BLINDPLACEBO-CONTROLLED TRIAL. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, 13(1), 18-23. SID. https://sid.ir/paper/306024/en

    Vancouver: Copy

    ABEDI SARA, TAEBI MAHBOUBEH, NASRE ESFAHANI MOHAMMADHOSEIN. EFFECT OF VITAMIN D SUPPLEMENTATION ON INTRACYTOPLASMICSPERM INJECTION OUTCOMES: A RANDOMIZED DOUBLE-BLINDPLACEBO-CONTROLLED TRIAL. INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY[Internet]. 2019;13(1):18-23. Available from: https://sid.ir/paper/306024/en

    IEEE: Copy

    SARA ABEDI, MAHBOUBEH TAEBI, and MOHAMMADHOSEIN NASRE ESFAHANI, “EFFECT OF VITAMIN D SUPPLEMENTATION ON INTRACYTOPLASMICSPERM INJECTION OUTCOMES: A RANDOMIZED DOUBLE-BLINDPLACEBO-CONTROLLED TRIAL,” INTERNATIONAL JOURNAL OF FERTILITY AND STERILITY, vol. 13, no. 1, pp. 18–23, 2019, [Online]. Available: https://sid.ir/paper/306024/en

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