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Information Journal Paper

Title

SERUM INSULIN-LIKE GROWTH FACTOR-I AND TUMOR SIZE IN PATIENTS WITH METASTATIC LIVER CANCER

Pages

  179-183

Abstract

 Background and Aims: Insulin-like growth factor-I (IGF-1) is a liver-derived humoral factor, which has important anabolic and metabolic actions. Low serum concentrations of IGF-1 have been reported in patients with chronic liver disease, especially cirrhosis and hepatocellular carcinoma and METASTATIC LIVER CANCER. The aim of our study was to evaluate any possible relationship between intensity of liver metastases on serum IGF-1 concentrations. Methods: Serum IGF-1 were measured by ELIZA (III) in10 patients with uninodular or multinodular liver metastases and extension £50% (group A) and 10 patients with multinodular or massive liver metastases and extension >50% (group B) of liver size without liver failure. Results: Serum IGF-1 concentration was significantly lower in the more sever metastatic group (group B) than the less sever metastatic group (group A) (121.40±52.08 vs. 210.30±42.59 ng/ml, respectively; P<0.001).Conclusions: Our findings suggest that the states of serum IGF-1 levels in patients with METASTATIC LIVER CANCER may be a helpful finding for determining the severity of metastasis to the liver.

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  • Cite

    APA: Copy

    MASOUDI, MASOUD, AGHAZADEH, R., SOUMI, M.H., SHAVAKHI, A., ARJMAND SHABESTARI, A., & ZALI, MOHAMMAD REZA. (2008). SERUM INSULIN-LIKE GROWTH FACTOR-I AND TUMOR SIZE IN PATIENTS WITH METASTATIC LIVER CANCER. HEPATITIS MONTHLY, 8(3), 179-183. SID. https://sid.ir/paper/306178/en

    Vancouver: Copy

    MASOUDI MASOUD, AGHAZADEH R., SOUMI M.H., SHAVAKHI A., ARJMAND SHABESTARI A., ZALI MOHAMMAD REZA. SERUM INSULIN-LIKE GROWTH FACTOR-I AND TUMOR SIZE IN PATIENTS WITH METASTATIC LIVER CANCER. HEPATITIS MONTHLY[Internet]. 2008;8(3):179-183. Available from: https://sid.ir/paper/306178/en

    IEEE: Copy

    MASOUD MASOUDI, R. AGHAZADEH, M.H. SOUMI, A. SHAVAKHI, A. ARJMAND SHABESTARI, and MOHAMMAD REZA ZALI, “SERUM INSULIN-LIKE GROWTH FACTOR-I AND TUMOR SIZE IN PATIENTS WITH METASTATIC LIVER CANCER,” HEPATITIS MONTHLY, vol. 8, no. 3, pp. 179–183, 2008, [Online]. Available: https://sid.ir/paper/306178/en

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