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Cites:

2

Information Journal Paper

Title

SHOULD A BOOSTER DOSE BE ADMINISTERED IN CHILDREN AFTER MASS IMMUNIZATION FOR HEPATITIS B?

Pages

  440-444

Abstract

 Background: Hepatitis B virus infection is a global health problem and vaccine-preventable disease, but the duration of the effects of HBV vaccination in infants is unknown.Objectives: The aim of this trial, which comprised children who had received 3 doses as part of the universal HBV IMMUNIZATION program and no additional doses, was to investigate anti-HBs titers and HBsAg status after 9 years.Patients and Methods: We performed a descriptive, cross-sectional field research study.The study sample, based on sociodemographics and minimum seroprevalence, was analyzed based on 10.00%±1.50 (95% confidence interval) (1150 individuals); trial was realized in a total of 1279 children (623 females and 656 males). Anti-HBs titers were measured by micro-EIA (Dia Sorin-Italy); titers<10 IU/mL were negative, 10-49 IU/mL were low-positive, and>50 IU/mL were high-positive. For anti-HBs titers below protective levels, HBsAg was measured by micro-EIA.Results: In approximately half of the children (48.5% in those living in semiurban areas and 42.3% in urban areas), antibody titers were below protective levels.Conclusions: Mass HBV vaccination, which was implemented in Turkey in 1998, significantly decreases HBsAg positivity in childhood. Nevertheless, it might be necessary to administer a BOOSTER dose after 8-9 years in children, especially those in low socioeconomic areas or in whom irregular/insufficient IMMUNIZATION is suspected.

Cites

References

Cite

APA: Copy

TOSUN, SELMA, DEVECI, SEROL, KAPLAN, YUNUS, & KASIRGA, ERHUN. (2011). SHOULD A BOOSTER DOSE BE ADMINISTERED IN CHILDREN AFTER MASS IMMUNIZATION FOR HEPATITIS B?. HEPATITIS MONTHLY, 11(6 (35)), 440-444. SID. https://sid.ir/paper/306404/en

Vancouver: Copy

TOSUN SELMA, DEVECI SEROL, KAPLAN YUNUS, KASIRGA ERHUN. SHOULD A BOOSTER DOSE BE ADMINISTERED IN CHILDREN AFTER MASS IMMUNIZATION FOR HEPATITIS B?. HEPATITIS MONTHLY[Internet]. 2011;11(6 (35)):440-444. Available from: https://sid.ir/paper/306404/en

IEEE: Copy

SELMA TOSUN, SEROL DEVECI, YUNUS KAPLAN, and ERHUN KASIRGA, “SHOULD A BOOSTER DOSE BE ADMINISTERED IN CHILDREN AFTER MASS IMMUNIZATION FOR HEPATITIS B?,” HEPATITIS MONTHLY, vol. 11, no. 6 (35), pp. 440–444, 2011, [Online]. Available: https://sid.ir/paper/306404/en

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