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Information Journal Paper

Title

SEROPREVALENCE OF HEPATITIS E AMONG IRANIAN RENAL TRANSPLANT RECIPI-ENTS

Pages

  646-651

Abstract

 Background: Renal transplant recipients are known to be susceptible to viral infections, with more severe clinical presentations compared to healthy persons. HEPATITIS E is generally a self-limited disease, which is caused by HEPATITIS E virus. Recently, HEPATITIS E has become more important in organ transplant recipients, because of new findings regarding the potential for chronic infections in this patient group.Objectives: This study aimed to evaluate the seroprevalence of ANTI-HEV IGG among kidney transplant recipients in Urmia, in the north-western region of Iran.Patients and Methods: 91 patients were selected randomly from amongst patients who had undergone kidney transplantation in Urmia, Iran. Each patient was tested for the presence of ANTI-HEV IGG antibody using an enzyme-linked immunosorbent assay (ELISA, Dia.Pro; Diagnostic Bioprobes, Italy).Results: 28 subjects (30.8%) were seropositive for ANTI-HEV IGG. Seropositive patients were generally older than seronegative patients (P=0.009). There was no correlation between HEV infection and the level of education (P=0.206), the history of blood transfusion (P=0.164), or history of pre-transplantation hemodialysis (P=0.228).There was no significant difference in the serum alanine aminotransferase (ALT) levels of the anti-HEV seropositive and seronegative patients. Multinomial logistic regression analysis indicated no significant relationship between HEV infection and increase in ALT levels, even after controlling for treatment with azathioprine (P=0.79, OR=1.12; 95% CI: 0.45–2.76).Conclusion: The ANTI-HEV IGG antibody has a high prevalence in Iranian kidney transplant recipients, and it is significantly higher in comparison with previous studies in the general population or in hemodialysis patients.

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    APA: Copy

    ROSTAMZADEH KHAMENEH, ZAKIEH, SEPEHRVAND, NARIMAN, & MASUDI, SIMA. (2011). SEROPREVALENCE OF HEPATITIS E AMONG IRANIAN RENAL TRANSPLANT RECIPI-ENTS. HEPATITIS MONTHLY, 11(8 (37)), 646-651. SID. https://sid.ir/paper/306441/en

    Vancouver: Copy

    ROSTAMZADEH KHAMENEH ZAKIEH, SEPEHRVAND NARIMAN, MASUDI SIMA. SEROPREVALENCE OF HEPATITIS E AMONG IRANIAN RENAL TRANSPLANT RECIPI-ENTS. HEPATITIS MONTHLY[Internet]. 2011;11(8 (37)):646-651. Available from: https://sid.ir/paper/306441/en

    IEEE: Copy

    ZAKIEH ROSTAMZADEH KHAMENEH, NARIMAN SEPEHRVAND, and SIMA MASUDI, “SEROPREVALENCE OF HEPATITIS E AMONG IRANIAN RENAL TRANSPLANT RECIPI-ENTS,” HEPATITIS MONTHLY, vol. 11, no. 8 (37), pp. 646–651, 2011, [Online]. Available: https://sid.ir/paper/306441/en

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