ASSOCIATION OF HFE GENE MUTATIONS WITH LIVER CIRRHOSIS DEPENDS ON INDUCTION OF IRON HOMEOSTASIS DISTURBANCES

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SIKORSKA KATARZYNA

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Journal Paper

Paper Information

Journal: Hepatitis Monthly Year:2012 | Volume:12 | Issue:3 Page(s): 213-214

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Information Journal Paper

Title

ASSOCIATION OF HFE GENE MUTATIONS WITH LIVER CIRRHOSIS DEPENDS ON INDUCTION OF IRON HOMEOSTASIS DISTURBANCES

Author(s)

SIKORSKA KATARZYNA | Issue Writer Certificate

Keywords

GENES

HOMEOSTASIS

LIVER CIRRHOSIS

Abstract

I read with the interest the paper by Jowkaret al. published in a recent issue of Hepatitis Monthly. The authors analysed the frequency of two HFE gene mutations in Iranian patients with a diagnosis of cryptogenic cirrhosis. In Europe, North America and Australia the homozygous C282Y mutation of the HFE gene is a major etiological factor associated with the pathoGENESis of progressive iron accumulation leading to multiorgan disfunction, as it is observed in hereditary hemochromatosis.About 5% of hereditary hemochromatosis cases in the Caucasian population are related to compound heterozygosity for C282Y and H63D mutations.

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APA: Copy

SIKORSKA, KATARZYNA. (2012). ASSOCIATION OF HFE GENE MUTATIONS WITH LIVER CIRRHOSIS DEPENDS ON INDUCTION OF IRON HOMEOSTASIS DISTURBANCES. HEPATITIS MONTHLY, 12(3), 213-214. SID. https://sid.ir/paper/306552/en

Vancouver: Copy

SIKORSKA KATARZYNA. ASSOCIATION OF HFE GENE MUTATIONS WITH LIVER CIRRHOSIS DEPENDS ON INDUCTION OF IRON HOMEOSTASIS DISTURBANCES. HEPATITIS MONTHLY[Internet]. 2012;12(3):213-214. Available from: https://sid.ir/paper/306552/en

IEEE: Copy

KATARZYNA SIKORSKA, “ASSOCIATION OF HFE GENE MUTATIONS WITH LIVER CIRRHOSIS DEPENDS ON INDUCTION OF IRON HOMEOSTASIS DISTURBANCES,” HEPATITIS MONTHLY, vol. 12, no. 3, pp. 213–214, 2012, [Online]. Available: https://sid.ir/paper/306552/en

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