INTRODUCING AN OPTIMAL LIVER ALLOCATION SYSTEM FOR LIVER CIRRHOSIS PATIENTS

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

ABOLGHASEMI JAMILEH; ESHRAGHIAN MOHAMMADREZA; NASIRI TOOSI MOHSEN; MAHMOODI MAHMOOD; RAHIMI FOROUSHANI ABBAS

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Hepatitis Monthly Year:2013 | Volume:13 | Issue:8 Page(s): 1-7

Download Full-Text

View:

418

Download:

129

Cites:

Information Journal Paper

Title

INTRODUCING AN OPTIMAL LIVER ALLOCATION SYSTEM FOR LIVER CIRRHOSIS PATIENTS

Author(s)

Keywords

LIVER TRANSPLANTATION

END-STAGE LIVER DISEASE

ALLOCATION

LIVER CIRRHOSIS

Abstract

Background: LIVER TRANSPLANTATION (LT) is the only treatment option for patients with advanced liver disease. Currently, liver donation to these patients, considering priorities, is based on the Model for END-STAGE LIVER DISEASE (MELD). MELD score is a tool for predicting the risk of mortality in patients with advanced liver disease. However, few studies have so far been conducted in Iran on the efficacy of MELD score of these patients.Objectives: This study reviews the present status of the MELD score and introduces a new model for optimal prediction of the risk of mortality in Iranian patients with advanced liver disease.Patients and Methods: Data required were collected from 305 patients with advanced liver disease who enrolled in a waiting list (WL) in Imam Khomeini Hospital from May 2008 to May 2009. All of the patients were followed up for at least 3 years until they died or underwent LT. Cox regression analysis was applied to select the factors affecting their mortality. Survival curves were plotted. Wilcoxson test and receiver operating characteristics curves for survival predictive model were used to compare the scores. All calculations were performed with the SPSS (version 13.0) and R soft wares.Results: During the study, 71 (23.3%) patients died due to LIVER CIRRHOSIS and 43 (14.1%) underwent LT. Viral Hepatitis (43.7%) is the most common cause of END-STAGE LIVER DISEASE among Iranian patients. A new model (NMELD) was proposed with the use of the natural logarithms of two blood serum variables (total bilirubin and albumin) and the patients' age (year) by applying the Cox model: NMELD = 10 × (0.736 × ln (bilirubin) – 1.312 × ln (albumin) + 0.025 × age + 1.776).Conclusions: The results of the Wilcoxon test showed that there is a significant difference between the usual MELD and our proposed NMELD scores (P<0.001). Receiver operating characteristics curve for survival predictive model indicated that the NMELD score is more efficient compared with the MELD score in predicting the risk of mortality. Since serum creatinine was not significant in NMELD score, further studies to clarify this issue are suggested.

Cites

References

No record.

Cite

APA: Copy

ABOLGHASEMI, JAMILEH, ESHRAGHIAN, MOHAMMADREZA, NASIRI TOOSI, MOHSEN, MAHMOODI, MAHMOOD, & RAHIMI FOROUSHANI, ABBAS. (2013). INTRODUCING AN OPTIMAL LIVER ALLOCATION SYSTEM FOR LIVER CIRRHOSIS PATIENTS. HEPATITIS MONTHLY, 13(8), 1-7. SID. https://sid.ir/paper/306687/en

Vancouver: Copy

ABOLGHASEMI JAMILEH, ESHRAGHIAN MOHAMMADREZA, NASIRI TOOSI MOHSEN, MAHMOODI MAHMOOD, RAHIMI FOROUSHANI ABBAS. INTRODUCING AN OPTIMAL LIVER ALLOCATION SYSTEM FOR LIVER CIRRHOSIS PATIENTS. HEPATITIS MONTHLY[Internet]. 2013;13(8):1-7. Available from: https://sid.ir/paper/306687/en

IEEE: Copy

JAMILEH ABOLGHASEMI, MOHAMMADREZA ESHRAGHIAN, MOHSEN NASIRI TOOSI, MAHMOOD MAHMOODI, and ABBAS RAHIMI FOROUSHANI, “INTRODUCING AN OPTIMAL LIVER ALLOCATION SYSTEM FOR LIVER CIRRHOSIS PATIENTS,” HEPATITIS MONTHLY, vol. 13, no. 8, pp. 1–7, 2013, [Online]. Available: https://sid.ir/paper/306687/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops