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Information Journal Paper

Title

THE ROLE OF AFLATOXINS IN HEPATOCELLULAR CARCINOMA

Pages

  0-0

Abstract

 Context: HEPATOCELLULAR CARCINOMA (HCC) is one of the most common cancers in the world but with a striking geographical variation in incidence; most of the burden is in developing countries. This geographic variation in HCC incidence might be due to geographic differences in the prevalence of various etiological factors.Evidence Acquisition: Here, we review the epidemiological evidence linking dietary exposure to aflatoxin B1 (AFB1) and risk of HCC, possible interactions between AFB1 and HEPATITIS B VIRUS (HBV) or polymorphisms of genes involved in AFB1-related metabolism as well as DNA repair.Results: Ecological, case-control and cohort studies that used various measures of aflatoxin exposure including dietary questionnaires, food surveys and biomarkers are summarized.Conclusions: Taken together, the data suggest that dietary exposure to AFLATOXINS is an important contributor to the high incidence of HCC in Asia and sub-Saharan Africa, where almost 82% of the cases occur.

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    • Cite

    APA: Copy

    WU, HUI CHEN, & SANTELLA, REGINA. (2012). THE ROLE OF AFLATOXINS IN HEPATOCELLULAR CARCINOMA. HEPATITIS MONTHLY, 12(10), 0-0. SID. https://sid.ir/paper/306805/en

    Vancouver: Copy

    WU HUI CHEN, SANTELLA REGINA. THE ROLE OF AFLATOXINS IN HEPATOCELLULAR CARCINOMA. HEPATITIS MONTHLY[Internet]. 2012;12(10):0-0. Available from: https://sid.ir/paper/306805/en

    IEEE: Copy

    HUI CHEN WU, and REGINA SANTELLA, “THE ROLE OF AFLATOXINS IN HEPATOCELLULAR CARCINOMA,” HEPATITIS MONTHLY, vol. 12, no. 10, pp. 0–0, 2012, [Online]. Available: https://sid.ir/paper/306805/en

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