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EVALUATION OF PREVALENCE AND RISK FACTORS OF HEPATITIS G VIRUS INFECTION AMONG HEMODIALYSIS PATIENTS REFERRED TO IRANIAN ARMY HOSPITALS IN TEHRAN DURING 2012-2013

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Abstract

 Background: GB VIRUS C (GBV-C) or hepatitis G virus (HGV) is a newly discovered and enveloped RNA positive-stranded flavivirus-like particle, which has not yet been proven to have major negative effects on liver.Objectives: Increasing the risk of blood-borne infections in hemodialysis patients is a main health care concern in different countries. Therefore, it is important to estimate the PREVALENCE and RISK FACTORS of hepatitis G virus infection in Iranian hemodialysis patients to design standard prevention and treatment plans.Patients and Methods: In this multicenter observational or epidemiologic study, 138 patients who underwent hemodialysis in Iranian Army hospitals in Tehran were included. Serum HIV antibody (Ab), HCV antibody and HBS antigen (Ag) were assessed. Demographic data such as gender, age, blood group, cause of renal failure, dialysis onset and duration were collected from medical files. GBV-C/HGV was evaluated by nested reverse transcription POLYMERASE CHAIN REACTION (RT-PCR) method. Then, all data were analyzed by SPSS ver. 13.Results: In total, 81 males and 57 females were included. The mean age of patients was 62.16±14.86 years. Six (4.3%) had positive results for GBV-C/HGV by RT-PCR. Except gender (P=0.045) and duration of dialysis in a week (P<0.001), other demographic factors revealed no significant difference (P>0.05). All patients had negative results for HIV Ab, HCV Ab and HBS Ag.Conclusions: Overall, 4.3% of patients had positive results for GBV-C/HGV and all negative for HIV, HCV and HBV. Further studies are needed to elucidate real PREVALENCE, RISK FACTORS and characteristics of HGV infection in Iranian hemodialysis patients.

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    APA: Copy

    DADMANESH, MARYAM, HOSSEINZADEH, MOHAMMAD, KEYVANI, HOSSEIN, GHORBAN, KHODAYAR, RAHIMI, MARYAM, HOSEINZADEH, MEHDI, & RANJBAR, MOHAMMAD MAHDI. (2015). EVALUATION OF PREVALENCE AND RISK FACTORS OF HEPATITIS G VIRUS INFECTION AMONG HEMODIALYSIS PATIENTS REFERRED TO IRANIAN ARMY HOSPITALS IN TEHRAN DURING 2012-2013. HEPATITIS MONTHLY, 15(1), 0-0. SID. https://sid.ir/paper/306887/en

    Vancouver: Copy

    DADMANESH MARYAM, HOSSEINZADEH MOHAMMAD, KEYVANI HOSSEIN, GHORBAN KHODAYAR, RAHIMI MARYAM, HOSEINZADEH MEHDI, RANJBAR MOHAMMAD MAHDI. EVALUATION OF PREVALENCE AND RISK FACTORS OF HEPATITIS G VIRUS INFECTION AMONG HEMODIALYSIS PATIENTS REFERRED TO IRANIAN ARMY HOSPITALS IN TEHRAN DURING 2012-2013. HEPATITIS MONTHLY[Internet]. 2015;15(1):0-0. Available from: https://sid.ir/paper/306887/en

    IEEE: Copy

    MARYAM DADMANESH, MOHAMMAD HOSSEINZADEH, HOSSEIN KEYVANI, KHODAYAR GHORBAN, MARYAM RAHIMI, MEHDI HOSEINZADEH, and MOHAMMAD MAHDI RANJBAR, “EVALUATION OF PREVALENCE AND RISK FACTORS OF HEPATITIS G VIRUS INFECTION AMONG HEMODIALYSIS PATIENTS REFERRED TO IRANIAN ARMY HOSPITALS IN TEHRAN DURING 2012-2013,” HEPATITIS MONTHLY, vol. 15, no. 1, pp. 0–0, 2015, [Online]. Available: https://sid.ir/paper/306887/en

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