HEPATOPROTECTIVE EFFECT OF 17β-ESTRADIOL AS ANTIOXIDANT MODULATORS AGAINST STRESS DAMAGE

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

CAN SERPIL; CIGSAR GULSEN; OZABACIGIL FATMA GUR; KARAMESE SELINA AKSAK; SELLI JALE; BACAK GULSUM; GEDIKLI SEMIN; SAHIN GONUL ZISAN; YIGIT SERDAR; CAN ISMAIL; GUL MUSTAFA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Hepatitis Monthly Year:2015 | Volume:15 | Issue:2 Page(s): 0-0

Download Full-Text

View:

480

Download:

283

Cites:

Information Journal Paper

Title

HEPATOPROTECTIVE EFFECT OF 17β-ESTRADIOL AS ANTIOXIDANT MODULATORS AGAINST STRESS DAMAGE

Author(s)

Keywords

ANTIOXIDANTS

EXERCISE

ESTROGENS

LIVER

Abstract

Background: LIVER is one of the most important organs affected by EXERCISE. According to the literature a few study to date has investigated the effects of estrogen supplementation on EXERCISE-induced oxidative stress in LIVER tissue of rats.Objectives: We aimed to investigate the effects of estrogen supplementation on oxidative stress markers in LIVER tissue of EXERCISEd rats.Materials and Methods: Male rats (n=35) were divided as estrogen supplemented (n=18) and non-supplemented groups (n=17); these groups were further divided as rest and eccentric EXERCISEd groups. Eccentric EXERCISE groups were further divided as rats killed after 1 hour and 48 hours of eccentric EXERCISE. Estrogen (10 mg/kg) was administered subcutaneously for 30 days. Eccentric EXERCISE was applied as treadmill run (15o downhill, 20 m/min) consisting of periods of 5 min run and 2 min rest repeated 18 times. The rat LIVER was examined biochemically and histologically. Activities of GST, GSH-Px, CAT, SOD and MDA concentration were also measured spectrophotometrically.Results: Some disruptions were detected in experimental groups compared with the control group. Additionally, EXERCISE training caused an increase in SOD and decrease in GSH-Px activities in some experimental groups. SOD activities increased significantly in group 3 (Estrogen (-), eccentric EXERCISE (+) killed (after 1 h), compared with group 5 (Estrogen (-), eccentric EXERCISE (+) killed (after 48 h). On the other hand, GSH-Px activities were also significantly decreased in groups 3, 4 and 5 compared with the control group. Leukocyte infiltration in LIVER increased after 48 hours compared with after 1 hour and estrogen supplementation was not able to prevent this infiltration.Conclusions: Estrogen seemed to be not very effective to prevent eccentric EXERCISE-induced LIVER damage.

Cites

THE PRETREATMENT EFFECTS OF ENDURANCE TRAINING ON DOXORUBICIN-INDUCED STRESS IN WISTER RATS

References

THE ROLE OF ANESTHETIC DRUGS IN LIVER APOPTOSIS

Cite

APA: Copy

CAN, SERPIL, CIGSAR, GULSEN, OZABACIGIL, FATMA GUR, KARAMESE, SELINA AKSAK, SELLI, JALE, BACAK, GULSUM, GEDIKLI, SEMIN, SAHIN, GONUL ZISAN, YIGIT, SERDAR, CAN, ISMAIL, & GUL, MUSTAFA. (2015). HEPATOPROTECTIVE EFFECT OF 17β-ESTRADIOL AS ANTIOXIDANT MODULATORS AGAINST STRESS DAMAGE. HEPATITIS MONTHLY, 15(2), 0-0. SID. https://sid.ir/paper/306892/en

Vancouver: Copy

CAN SERPIL, CIGSAR GULSEN, OZABACIGIL FATMA GUR, KARAMESE SELINA AKSAK, SELLI JALE, BACAK GULSUM, GEDIKLI SEMIN, SAHIN GONUL ZISAN, YIGIT SERDAR, CAN ISMAIL, GUL MUSTAFA. HEPATOPROTECTIVE EFFECT OF 17β-ESTRADIOL AS ANTIOXIDANT MODULATORS AGAINST STRESS DAMAGE. HEPATITIS MONTHLY[Internet]. 2015;15(2):0-0. Available from: https://sid.ir/paper/306892/en

IEEE: Copy

SERPIL CAN, GULSEN CIGSAR, FATMA GUR OZABACIGIL, SELINA AKSAK KARAMESE, JALE SELLI, GULSUM BACAK, SEMIN GEDIKLI, GONUL ZISAN SAHIN, SERDAR YIGIT, ISMAIL CAN, and MUSTAFA GUL, “HEPATOPROTECTIVE EFFECT OF 17β-ESTRADIOL AS ANTIOXIDANT MODULATORS AGAINST STRESS DAMAGE,” HEPATITIS MONTHLY, vol. 15, no. 2, pp. 0–0, 2015, [Online]. Available: https://sid.ir/paper/306892/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops