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Information Journal Paper

Title

PERSISTENCE OF ANTI-HBS AMONG PALESTINIAN MEDICAL STUDENTS AFTER 18 - 22 YEARS OF VACCINATION: A CROSS-SECTIONAL STUDY

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  0-0

Abstract

 Background: Hepatitis B infection is a global public health problem affecting various sectors in the society. Vaccination is the first line measure to prevent the disease.Objectives: To assess the persistence of anti-HBs marker among medical students after 18 - 22 of vaccination as an indicator for HEPATITIS B VIRUS vaccine efficacy.Patients and Methods: In this study, 249 Palestinian medical students vaccinated at birth, 1, and 6 months of age using Engerix™-B starting from 1992 were studied. About 58% (144.249) of the students were Palestinians holding Israeli citizenship, while 42% (105.249) were Palestinians from the West Bank. Students were tested serologically for anti-HBs, as a marker for vaccine-induced immunity.Results: Over 75% (188/248) of students had levels of anti-HBs greater than 10 mIU/mL indicating immunity and protection. Five cases had positive results for anti-HBc indicating exposure to HBV infection; however, none of these cases showed any sign of HBV-DNA indicating effective clearance of the virus by the vaccine. Around 57% of the study group had anti-HBs level of 100 - 1000 mIU/mL. No significant association was found between anti-HBs level and age, sex, locality and level of anti-HBc (P > 0.05). The students were aware of different aspects of hepatitis B infection regarding the virus, symptoms, prevention and mode of transmission.Conclusions: The Palestinian and Israeli official policies to give a booster dose for risk groups like medical students at anti-HBs level below 10 mIU/mL should continue to ensure absolute protection. The currently-used vaccine and its time program cleared virus from students believed to have been exposed to the virus during their lifetime.

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    APA: Copy

    DUMAIDI, KAMAL, & AL JAWABREH, AMER. (2015). PERSISTENCE OF ANTI-HBS AMONG PALESTINIAN MEDICAL STUDENTS AFTER 18 - 22 YEARS OF VACCINATION: A CROSS-SECTIONAL STUDY. HEPATITIS MONTHLY, 15(11), 0-0. SID. https://sid.ir/paper/306917/en

    Vancouver: Copy

    DUMAIDI KAMAL, AL JAWABREH AMER. PERSISTENCE OF ANTI-HBS AMONG PALESTINIAN MEDICAL STUDENTS AFTER 18 - 22 YEARS OF VACCINATION: A CROSS-SECTIONAL STUDY. HEPATITIS MONTHLY[Internet]. 2015;15(11):0-0. Available from: https://sid.ir/paper/306917/en

    IEEE: Copy

    KAMAL DUMAIDI, and AMER AL JAWABREH, “PERSISTENCE OF ANTI-HBS AMONG PALESTINIAN MEDICAL STUDENTS AFTER 18 - 22 YEARS OF VACCINATION: A CROSS-SECTIONAL STUDY,” HEPATITIS MONTHLY, vol. 15, no. 11, pp. 0–0, 2015, [Online]. Available: https://sid.ir/paper/306917/en

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