EVALUATION OF SERUM AND SPUTUM LEVEL OF IL-21 IN SARDASHT CHEMICAL VICTIMS AND ITS RELATIONSHIP WITH LONG-TERM PULMONARY COMPLICATIONS (27 YEARS AFTER SULFUR MUSTARD EXPOSURE)

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MOHSENI MAJD ALI MOHAMMAD; GHAZANFARI TOOBA; DILMAGHANIAN RAZIYEH

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Journal: DANESHVAR MEDICINE Year:2017 | Volume:24 | Issue:129 Page(s): 1-8

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Title

EVALUATION OF SERUM AND SPUTUM LEVEL OF IL-21 IN SARDASHT CHEMICAL VICTIMS AND ITS RELATIONSHIP WITH LONG-TERM PULMONARY COMPLICATIONS (27 YEARS AFTER SULFUR MUSTARD EXPOSURE)

Author(s)

MOHSENI MAJD ALI MOHAMMAD | GHAZANFARI TOOBA | DILMAGHANIAN RAZIYEH | Issue Writer Certificate

Keywords

SULFUR MUSTARDQ3

PULMONARY COMPLICATIONQ2

IL-21Q1

CHEMICAL VICTIMSQ2

SARDASHTQ2

Abstract

Background and Objectives: PULMONARY COMPLICATIONs are one of the most important long-term SULFUR MUSTARD (SM) exposure that CHEMICAL VICTIMS are suffering for years. IL-21 is one of the important cytokines contributing in chronic pulmonary inflammatory diseases. In this study, the serum and sputum levels of IL-21 and their correlations with PULMONARY COMPLICATIONs was evaluated 27 years after SULFUR MUSTARD exposure.Materials and Methods: Final sample size was 475 (350 men and 125 women) SM exposed and 150 (100 men and 50 women from Rabat) unexposed controls.The age span of volunteers was 27-67 years.Results: There was no significant different between exposed and control groups in serum and sputum levels of IL-21, but the serum level of IL-21 showed a significant correlation with spirometry parameter (FEV1/FVC) in SM exposed group was observed.Conclusion: The affected serum and sputum levels of IL-21 by SULFUR MUSTARD exposure were not variable, but there was a significant negative correlation between serum level of IL-21and FEV1/FVC in SM exposed group.

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References

MIOSSEC P. IL-17 IN CHRONIC INFLAMMATION: FROM DISCOVERY TO TARGETING

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APA: Copy

MOHSENI MAJD, ALI MOHAMMAD, GHAZANFARI, TOOBA, & DILMAGHANIAN, RAZIYEH. (2017). EVALUATION OF SERUM AND SPUTUM LEVEL OF IL-21 IN SARDASHT CHEMICAL VICTIMS AND ITS RELATIONSHIP WITH LONG-TERM PULMONARY COMPLICATIONS (27 YEARS AFTER SULFUR MUSTARD EXPOSURE). DANESHVAR MEDICINE, 24(129), 1-8. SID. https://sid.ir/paper/30753/en

Vancouver: Copy

MOHSENI MAJD ALI MOHAMMAD, GHAZANFARI TOOBA, DILMAGHANIAN RAZIYEH. EVALUATION OF SERUM AND SPUTUM LEVEL OF IL-21 IN SARDASHT CHEMICAL VICTIMS AND ITS RELATIONSHIP WITH LONG-TERM PULMONARY COMPLICATIONS (27 YEARS AFTER SULFUR MUSTARD EXPOSURE). DANESHVAR MEDICINE[Internet]. 2017;24(129):1-8. Available from: https://sid.ir/paper/30753/en

IEEE: Copy

ALI MOHAMMAD MOHSENI MAJD, TOOBA GHAZANFARI, and RAZIYEH DILMAGHANIAN, “EVALUATION OF SERUM AND SPUTUM LEVEL OF IL-21 IN SARDASHT CHEMICAL VICTIMS AND ITS RELATIONSHIP WITH LONG-TERM PULMONARY COMPLICATIONS (27 YEARS AFTER SULFUR MUSTARD EXPOSURE),” DANESHVAR MEDICINE, vol. 24, no. 129, pp. 1–8, 2017, [Online]. Available: https://sid.ir/paper/30753/en

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