SURVEYING THE CHRONIC COMPLICATIONS OF MUSTARD GAS ON LYMPHOCYTE B BY MEANS OF SURFACE MARKERS

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HAMZEPOUR SH.; MOHAMMAD HASAN ZOHEYR; SHAKER Z.

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Journal: Research in Medicine Year:2003 | Volume:27 | Issue:3 Page(s): 233-238

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Information Journal Paper

Title

SURVEYING THE CHRONIC COMPLICATIONS OF MUSTARD GAS ON LYMPHOCYTE B BY MEANS OF SURFACE MARKERS

Author(s)

HAMZEPOUR SH. | MOHAMMAD HASAN ZOHEYR | SHAKER Z. | Issue Writer Certificate

Keywords

MUSTARD GASQ3

B CELLSQ2

Abstract

Background: MUSTARD GAS may cause acute (early) and chronic (late) lesions. Acute lesions include disseminated bullous lesions on skin, respiratory, and GI disorders; chronic complications are chronic bronchitis, severe asthma, and malignancies. B CELLS are active part of humoral immunity that secrete antibodies to defend our body.Materials and methods: We have evaluated 3 groups of patients, each including 25 patients as well as 10 control subjects. Complete blood count, morphological and flowcytometric studies were carried out. For flowcytometric studies 4 markers of CD45, CD19, HLA-DR, and CD25 were assessed on surface of B CELLS with CD45/CD19/HLA-DR phenotype. Their performance was investigated with CD25.Results: Our findings have revealed a significant decrease in CD25 on B CELLS' surface that is associated with recurrent microbial infections, in patients exposed to MUSTARD GAS.Conclusion: Genetic changes in B CELLS, due to MUSTARD GAS inhalation may predispose individuals to recurrent infections such as pneumonia.

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APA: Copy

HAMZEPOUR, SH., MOHAMMAD HASAN, ZOHEYR, & SHAKER, Z.. (2003). SURVEYING THE CHRONIC COMPLICATIONS OF MUSTARD GAS ON LYMPHOCYTE B BY MEANS OF SURFACE MARKERS. PAJOUHESH DAR PEZESHKI, 27(3), 233-238. SID. https://sid.ir/paper/42075/en

Vancouver: Copy

HAMZEPOUR SH., MOHAMMAD HASAN ZOHEYR, SHAKER Z.. SURVEYING THE CHRONIC COMPLICATIONS OF MUSTARD GAS ON LYMPHOCYTE B BY MEANS OF SURFACE MARKERS. PAJOUHESH DAR PEZESHKI[Internet]. 2003;27(3):233-238. Available from: https://sid.ir/paper/42075/en

IEEE: Copy

SH. HAMZEPOUR, ZOHEYR MOHAMMAD HASAN, and Z. SHAKER, “SURVEYING THE CHRONIC COMPLICATIONS OF MUSTARD GAS ON LYMPHOCYTE B BY MEANS OF SURFACE MARKERS,” PAJOUHESH DAR PEZESHKI, vol. 27, no. 3, pp. 233–238, 2003, [Online]. Available: https://sid.ir/paper/42075/en

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