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Information Journal Paper

Title

URINARY INTERLEUKIN-8 IN ACUTE PYELONEPHRITIS OF CHILDREN A BEFORE-AFTER STUDY

Pages

  193-196

Abstract

 Introduction. The aim of this study was to assess urinary INTERLEUKIN-8 (IL-8) levels in pyelonephritis and its relation with the clinical course of the infection and of inflammatory changes detected by renal scintigraphy.  Materials and Methods. In this quasi-experimental before-after study, we evaluated 91 CHILDren aged 1 to 144 months (mean 34.4 ± 35.2 months) with pyelonephritis. Inflammatory markers including erythrocyte sedimentation rate, C-reactive protein, leukocyte count, and urinary IL-8, together with the results of ultrasonography, voiding cystourethrography, and dimercaptosuccinic acid renal scintigraphy were evaluated in these CHILDren. The ratios of urinary IL-8 to creatinine (IL-8/C) before and after the treatment were compared with each other. Results. Urinary IL-8/C levels were significantly higher after the empirical treatment in comparison with those before the treatment (0.19 ± 0.21 versus 0.51 ± 0.53, P < .001). No correlation was found between the urinary IL-8 levels and leukocyturia, urine culture results, other inflammatory markers, or findings of imaging examinations.Conclusions. We found high urinary IL-8 levels in CHILDren with pyelonephritis. We also documented its increasing after the treatment. We conclude that evaluation of urinary IL-8 can be a noninvasive test for diagnosis of upper urinary tract infection and its response to treatment.  

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    APA: Copy

    MOHKAM, M., KARIMI, ABD ELAH, KARIMI, HOSSEIN, SHARIFIAN, MOSTAFA, ARMIN, SH., DALIRANI, REZA, & ABD ELAH GORJI, F.. (2008). URINARY INTERLEUKIN-8 IN ACUTE PYELONEPHRITIS OF CHILDREN A BEFORE-AFTER STUDY. IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD), 2(4), 193-196. SID. https://sid.ir/paper/308704/en

    Vancouver: Copy

    MOHKAM M., KARIMI ABD ELAH, KARIMI HOSSEIN, SHARIFIAN MOSTAFA, ARMIN SH., DALIRANI REZA, ABD ELAH GORJI F.. URINARY INTERLEUKIN-8 IN ACUTE PYELONEPHRITIS OF CHILDREN A BEFORE-AFTER STUDY. IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD)[Internet]. 2008;2(4):193-196. Available from: https://sid.ir/paper/308704/en

    IEEE: Copy

    M. MOHKAM, ABD ELAH KARIMI, HOSSEIN KARIMI, MOSTAFA SHARIFIAN, SH. ARMIN, REZA DALIRANI, and F. ABD ELAH GORJI, “URINARY INTERLEUKIN-8 IN ACUTE PYELONEPHRITIS OF CHILDREN A BEFORE-AFTER STUDY,” IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD), vol. 2, no. 4, pp. 193–196, 2008, [Online]. Available: https://sid.ir/paper/308704/en

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