مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Information Journal Paper

Title

ROLE OF VITAMIN A IN PREVENTING RENAL SCARRING AFTER ACUTE PYELONEPHRITIS

Pages

  320-323

Abstract

 Introduction: The role of VITAMIN A in re-epithelialization of the damaged mucosal surfaces has been documented. The aim of this study was to evaluate the role of VITAMIN A in preventing renal scaring after acute PYELONEPHRITIS in CHILDren.Materials and Methods: This clinical trial study was conducted in CHILDren with acute PYELONEPHRITIS in Mofid CHILDren Hospital (Tehran, Iran). Patients were randomly divided into two groups to receive ceftriaxone and VITAMIN A or ceftriaxone only. Dimercaptosuccinic acid (DMSA) renal scintigraphy was performed before the start of the treatment and 6 months later. Results were compared for renal scaring between the two groups.Results: Seventy-six patients (11 boys and 65 girls) were enrolled. The mean age was 25±24 months and 54 patients (71.1%) were under 2 years old. The average VITAMIN A level was 71±24 mg/ dL in the treatment group and it was 62±18 mg/dL in the control group. Baseline DMSA scans were comparable between the two groups in terms of scarring (P=0.53), but the second DMSA scans showed a significant change in progression of the renal injury and scaring in the control group compared to those treated with VITAMIN A as well as antibiotic (P<0.001).Conclusions: We found administration of the VITAMIN A was useful in decreasing the amount of the injury and scarring following the PYELONEPHRITIS. Based on our study, VITAMIN A can be used in conjunction with other treatments in the management of acute PYELONEPHRITIS in CHILDren.

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    APA: Copy

    DALIRANI, REZA, YOUSEFI ZOSHK, MOJTABA, SHARIFIAN, MOSTAFA, MOHKAM, MASOUMEH, KARIMI, ABDOLLAH, FAHIMZAD, ALIREZA, & VARZANDEFAR, MONA. (2011). ROLE OF VITAMIN A IN PREVENTING RENAL SCARRING AFTER ACUTE PYELONEPHRITIS. IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD), 5(5), 320-323. SID. https://sid.ir/paper/309344/en

    Vancouver: Copy

    DALIRANI REZA, YOUSEFI ZOSHK MOJTABA, SHARIFIAN MOSTAFA, MOHKAM MASOUMEH, KARIMI ABDOLLAH, FAHIMZAD ALIREZA, VARZANDEFAR MONA. ROLE OF VITAMIN A IN PREVENTING RENAL SCARRING AFTER ACUTE PYELONEPHRITIS. IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD)[Internet]. 2011;5(5):320-323. Available from: https://sid.ir/paper/309344/en

    IEEE: Copy

    REZA DALIRANI, MOJTABA YOUSEFI ZOSHK, MOSTAFA SHARIFIAN, MASOUMEH MOHKAM, ABDOLLAH KARIMI, ALIREZA FAHIMZAD, and MONA VARZANDEFAR, “ROLE OF VITAMIN A IN PREVENTING RENAL SCARRING AFTER ACUTE PYELONEPHRITIS,” IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD), vol. 5, no. 5, pp. 320–323, 2011, [Online]. Available: https://sid.ir/paper/309344/en

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