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Information Journal Paper

Title

ASSOCIATION BETWEEN 25-HYDROXYVITAMIN D LEVEL AND INFLAMMATORY AND NUTRITIONAL FACTORS IN HEMODIALYSIS AND PERITONEAL DIALYSIS PATIENTS IN QOM, IRAN

Pages

  205-212

Abstract

 Introduction: This study aimed to evaluate the prevalence of VITAMIN D inadequacy in patients receiving maintenance hemodialysis and peritoneal DIALYSIS (PD) and its association with inflammatory and nutritional factors.Materials and Methods: A total of 176 hemodialysis and 32 PD patients participated in the study. Serum levels of 25-hydroxyvitamin D, albumin, parathyroid hormone, calcium, phosphorus, highsensitivity C-reactive protein (HSCRP), and neutrophil-lymphocyte ratio (NLR) were measured. Data on body mass index were also collected. Stepwise multiple logistic regression analysis was used to identify predictors for 25-hydroxyvitamin D deficiency and its relationship with the nutritional and inflammatory factors.Results: No significant association was found between 25-hydroxyvitamin D and age, body mass index, serum calcium, serum phosphorus, parathyroid hormone, serum albumin, DIALYSIS quality, and duration of DIALYSIS; while NLR and HSCRP were significantly associated with 25-hydroxyvitamin D in the hemodialysis patients only (P<.001 and P=.001, respectively). A positive correlation was found between NLR and HSCRP in both hemodialysis and PD patients. (r=0.817; P<.001). This association was confirmed between an NLR greater than 3 and an HSCRP level greater than 3.Conclusions: VITAMIN D deficiency was highly prevalent in our DIALYSIS patients, and inadequate level of VITAMIN D was associated with inflammatory factors such as HSCRP and NLR in both hemodialysis and PD patients. An easy and inexpensive test of an NLR greater than 3 could be used as a measure of INFLAMMATION instead of HSCRP in both PD and hemodialysis patients.

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    APA: Copy

    MIRCHI, ELHAM, SAGHAFI, HOSSEIN, GHAREHBEGLOU, MOHAMMAD, AGHAALI, MOHAMMAD, REZAIAN, ZAHRA, & GHAVIAHD, MASOOMEH. (2016). ASSOCIATION BETWEEN 25-HYDROXYVITAMIN D LEVEL AND INFLAMMATORY AND NUTRITIONAL FACTORS IN HEMODIALYSIS AND PERITONEAL DIALYSIS PATIENTS IN QOM, IRAN. IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD), 10(4), 205-212. SID. https://sid.ir/paper/309504/en

    Vancouver: Copy

    MIRCHI ELHAM, SAGHAFI HOSSEIN, GHAREHBEGLOU MOHAMMAD, AGHAALI MOHAMMAD, REZAIAN ZAHRA, GHAVIAHD MASOOMEH. ASSOCIATION BETWEEN 25-HYDROXYVITAMIN D LEVEL AND INFLAMMATORY AND NUTRITIONAL FACTORS IN HEMODIALYSIS AND PERITONEAL DIALYSIS PATIENTS IN QOM, IRAN. IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD)[Internet]. 2016;10(4):205-212. Available from: https://sid.ir/paper/309504/en

    IEEE: Copy

    ELHAM MIRCHI, HOSSEIN SAGHAFI, MOHAMMAD GHAREHBEGLOU, MOHAMMAD AGHAALI, ZAHRA REZAIAN, and MASOOMEH GHAVIAHD, “ASSOCIATION BETWEEN 25-HYDROXYVITAMIN D LEVEL AND INFLAMMATORY AND NUTRITIONAL FACTORS IN HEMODIALYSIS AND PERITONEAL DIALYSIS PATIENTS IN QOM, IRAN,” IRANIAN JOURNAL OF KIDNEY DISEASES (IJKD), vol. 10, no. 4, pp. 205–212, 2016, [Online]. Available: https://sid.ir/paper/309504/en

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